Publications by authors named "Nitish K Singh"
Article Synopsis
- - The study investigates how trace elements (like zinc and magnesium) relate to inflammation markers (TNF-α and IL-6) in children with short stature, aiming to identify potential causes for this condition.
- - Researchers analyzed 220 samples, revealing lower levels of zinc and magnesium and higher copper levels in short-statured individuals, with a notable correlation between these trace elements and inflammation markers.
- - The findings suggest that monitoring the Cu/Zn ratio and inflammation markers could help identify children at risk for short stature, and zinc supplementation might improve growth by reducing inflammation.
Article Synopsis
- Neural tube defects (NTDs) are serious central nervous system disorders that arise from the failure of the neural tube to close during embryonic development and can have significant health impacts when not diagnosed early.
- The study investigates the link between maternal and child NTDs and prenatal exposure to trace elements like copper (Cu) and zinc (Zn), as well as variations in the MTHFR gene related to folate metabolism.
- Findings show significant associations between specific MTHFR genotypes and NTD risk, as well as notable differences in trace element levels between individuals with NTDs and healthy controls.*
Background and objective Down syndrome (DS) is characterized by the presence of an additional chromosome; it is a typical chromosomal disorder causing intellectual disability in individuals. The diagnostic process for DS often involves conventional karyotyping, which can be time-consuming. Trisomy 21 and other chromosomal abnormalities may now be quickly and accurately diagnosed using quantitative fluorescence polymerase chain reaction (QF-PCR).
View Article and Find Full Text PDFBackground And Objectives: India had faced a devastating second outbreak of COVID-19 infection, in which a majority of the viral sequences were found to be of the B.1.617.
View Article and Find Full Text PDFThe polygalacturonases (PG) is one of the important members of pectin-degrading glycoside hydrolases of the family GH28. In plants, PG represents multigene families associated with diverse processes. In the present study, an attempt has been made to investigate the diversity of PG genes among monocots and dicots with respect to phylogeny, gene duplication and subcellular localization to get an insight into the evolutionary and functional attributes.
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