Publications by authors named "Nitin Ade"
Article Synopsis
- Microneedle (MN) technology, particularly hydrogel-forming microneedles (HFMNs), offers an innovative non-invasive method for delivering drugs through the skin, promising significant improvements in treating various dermatological conditions like acne and psoriasis.!* -
- HFMNs are composed of small needles made from hydrophilic polymers that can penetrate the skin’s outer layer without harming underlying tissues; they absorb fluid to form a hydrogel that aids in transporting therapeutic agents directly into the dermal microcirculation.!* -
- The technology is designed to reduce patient discomfort compared to traditional needles, enabling better drug delivery with controlled release profiles, and it also allows for real-time monitoring of interstitial fluid, enhancing the
The main objective of this review is to provide a comprehensive overview of the current evidence regarding the use of chitosan-based hydrogels to manage skin infections. Chitosan, a naturally occurring polysaccharide derived from chitin, possesses inherent antimicrobial properties, making it a promising candidate for treating various dermal infections. This review follows a systematic approach to analyze relevant studies that have investigated the effectiveness of chitosan-based hydrogels in the context of dermal infections.
View Article and Find Full Text PDFChito-oligosaccharides (COS), derived from chitosan (CH), are attracting increasing attention as drug delivery carriers due to their biocompatibility, biodegradability, and mucoadhesive properties. Grafting, the process of chemically modifying CH/COS by adding side chains, has been used to improve their drug delivery performance by enhancing their stability, targeted delivery, and controlled release. In this review, we aim to provide an in-depth study on the recent advances in the grafting of CH/COS for multifarious applications.
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