Bleeding and thrombosis in high-risk renal transplantation candidates using heparin.

Background: Heparin can reduce the risk of renal artery/vein thrombosis in renal transplant patients with hypercoagulable states (HCS), but is associated with a high bleeding risk. Little is known about risk factors for this bleeding risk or the optimal anticoagulation target.

Objective: To determine factors associated with this bleeding risk and determine the optimal partial thromboplastin time (PTT) ratio.