Chest Pain as a Symptom of Early-Onset Metastatic Prostate Cancer: Exploring the Role of Screening.

Prostate cancer is one of the most prevalent malignancies affecting males, primarily occurring in older men. However, it has been observed that there is a growing trend of new cases among younger individuals. We present the case of a 35-year-old male who had experienced persistent, severe right-sided chest pain for three months, unrelieved by analgesics.

A Solid-Phase Approach to Accessing Bisthioether-Stapled Peptides Resulting in a Potent Inhibitor of PRC2 Catalytic Activity.

Stapled peptides have emerged as a new class of therapeutics to effectively target intractable protein-protein interactions. Thus, efficient and versatile methods granting easy access to this class of compounds and expanding the scope(s) of the currently available ones are of great interest. Now, a solid phase approach is described for the synthesis of bisthioether stapled peptides with multiple architectures, including single-turn, double-turn, and double-stapled macrocycles.

[The centenary of the first medical meeting in Eretz Israel--the Trachoma Conference of 1914].

In the spring of 1914 the Jewish physicians in Eretz Israel held their first professional conference in Jerusalem. A total of 24 out of 48 doctors participated. The subject of the conference was trachoma, a common eye disease and a major cause of blindness in the Middle East.

[The centenary of the Israel Medical Association].

On January 12th 1912, six Jewish physicians and one pharmacist assembled in Tel-Aviv to proclaim the founding of the Jaffa Hebrew Medical Society. One year later the Jewish doctors of Jerusalem established the "Society of Hebrew Speaking Physicians". On 28th December, 1918 a few weeks after the end of World War 1, both organizations merged into the Hebrew Medical Association which later became the Israel Medical Association (I.

[Dr. Kurt Steinitz (1907-1966) and the 60th anniversary of the first hemodialysis in the Middle East].

The 60th anniversary of Israel coincides with the advent of the first hemodialysis in the Middle East. It was performed by Dr. Kurt Steinitz--a Jewish immigrant from Breslau, then in Germany.

[To Russia with love: ambulances and medical equipment from Eretz Israel to the Red Army].

During the autumn of 1942 the attention of the entire world was concentrated on the decisive struggle at the Eastern Front between the Wehrmacht and the Red Army. The profound sympathies of the "Yishuv" towards Russia derived not only from the common cause--the defeat of Germany but also from the Eastern European mentality, similar socialistic ideology and culture of a significant part of the immigrants. Dr.