Publications by authors named "Nismat Javed"

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  • * Frailty, which indicates a decline in health, is a key predictor of negative outcomes for older adults, affecting hospitalization rates and recovery, and is relevant in assessing risks for various diseases including cancer, heart disease, and dementia.
  • * The article discusses how frailty indices can help forecast complications, mortality, and long-term health outcomes across different health issues, suggesting that future healthcare approaches should incorporate frailty assessments to improve patient care and reduce adverse effects.
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  • - This study investigates differences in clinical features and outcomes of non-acute myocardial infarction-associated cardiogenic shock (nAMI-CS) between Hispanic and non-Hispanic patients in the U.S. using data from hospitalizations between 2018 and 2020.
  • - Out of 8607 hospitalizations, 832 (9.6%) were Hispanic, who presented as younger and with more co-morbidities like diabetes and heart failure, while having a slightly higher in-hospital mortality rate (18.6% vs. 17%).
  • - Hispanic patients experienced longer hospital stays and higher treatment costs compared to non-Hispanic patients, indicating the need for further research to explore the reasons behind these health disparities.
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() infection is a widespread global health issue with a varying prevalence influenced by geography, socioeconomic status, and demographics. In the U.S.

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  • GLP-1 receptor agonists are commonly used in diabetes and obesity treatment, but their use may increase the risk of gastroparesis and aspiration during surgical or endoscopic procedures, leading to recent guidelines recommending their discontinuation before surgery.
  • A study at BronxCare Health System analyzed data from 306 patients, comparing those on clear liquid diets versus regular diets before endoscopic procedures, focusing on gastric residue and aspiration risks.
  • Results indicated that patients on clear liquid diets had significantly less gastric residue compared to those on regular diets, suggesting that a 24-hour liquid diet is safe before such procedures, with no reported complications.
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Gastrointestinal diseases are increasing in global prevalence. As a result, the contribution to both mortality and healthcare costs is increasing. While interventions utilizing scoping techniques or ultrasound are crucial to both the timely diagnosis and management of illness, a few limitations are associated with these techniques.

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infections have emerged as now a common nosocomial pathogen. Most of the infections manifest in patients with underlying medical conditions. The features of infection can range from infections in the lower urinary tract, respiratory tract, gastrointestinal disease, or bacteremia, however renal abscesses remain uncommon.

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  • Takotsubo syndrome (TTS) is a temporary heart condition characterized by ballooning of the heart's apex, often triggered by emotional or physical stress and associated with factors like sympathetic stimulation and certain medications.
  • Diagnosis includes checking specific heart activity patterns and using imaging techniques like angiography to rule out other heart issues.
  • A case report highlighted a 61-year-old woman with a history of TTS who experienced a recurrence during hospitalization, emphasizing the need for quick diagnosis and treatment to improve patient outcomes, especially in critical situations.
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Lyme disease often leads to cardiac injury and electrophysiological abnormalities. This study aimed to explore links between atrioventricular blocks and additional arrhythmias in Lyme carditis patients. This systematic review and meta-analysis of existing literature was performed from 1990 to 2023, and aimed to identify cases of Lyme carditis through serology or clinical diagnosis with concomitant arrhythmias.

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Heart failure is a complex clinical syndrome that is one of the causes of high mortality worldwide. Additionally, healthcare systems around the world are also being burdened by the aging population and subsequently, increasing estimates of patients with heart failure. As a result, it is crucial to determine novel ways to reduce the healthcare costs, rate of hospitalizations and mortality.

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Mucosal Schwann cell hamartomas (MSCHs) are non-common noncancerous growths derived from Schwann cells in the peripheral nervous system, often found unexpectedly during routine colonoscopy examinations. These growths primarily occur in the colon, although they can also appear in the esophagus and are not linked to familial cancer syndromes. Diagnosis relies on specific histological characteristics and staining patterns.

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  • * Steatosis, the initial stage of MAFLD, is closely associated with metabolic syndrome, highlighting the roles of insulin resistance, high-calorie diets, and lipid metabolism disturbances in liver fat accumulation.
  • * Liver fibrosis is a key predictor of MASH progression and liver cancer (HCC), necessitating targeted treatment strategies and improved surveillance due to various risk factors like age, gender, and lifestyle that contribute to HCC development.
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Background: Pericardial effusion is associated with amyloidosis, specifically amyloid light chain (AL) and transthyretin (ATTR) subtypes. However, the patients might present with different clinical symptoms.

Objective: To determine the characteristics and associations of patients with pericardial effusion owing to either AL or ATTR amyloidosis.

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This case study reviews a 48-year-old Hispanic male working in construction who presented with left upper medial thigh pain, redness, and swelling after exposure to hazardous chemicals during cement processing. Initially diagnosed with cellulitis and adjacent myositis, the patient met sepsis criteria and received empiric antibiotics. However, negative cultures and an evolving wound appearance shifted the diagnosis towards bullous diseases and chemical injury.

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Stroke is an infarction of the central nervous system (brain, spinal cord, or retina) that results from a disruption in cerebral blood flow either due to ischemia or hemorrhage. Complications of acute stroke are common and include pneumonia, urinary tract infection, myocardial infarction, deep vein thrombosis, and pulmonary embolism, among several others, all of which increase the risk of poor clinical outcomes. Gastrointestinal bleeding is a well-known complication that can occur during the acute phase of stroke.

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Granulomatous interstitial nephritis is a rare form of tubulointerstitial nephritis and has been uncommonly observed with clozapine usage. Additionally, the progression of the disease to manifest as renal failure requiring dialysis is also uncommon. We describe a case of a 56-year-old female who presented with syncope and was diagnosed with granulomatous interstitial nephritis on biopsy.

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Introduction There is considerable evidence to suggest the role of thyroid hormone in acute coronary syndrome (ACS), but less is known about its prognostic role in heart failure (HF). We aimed to assess the role of global longitudinal strain (GLS) in patients hospitalized with HF and underlying subclinical hypothyroidism (SCHS). Methods A retrospective analysis of 161 subjects was conducted by dichotomizing them into HF with preserved ejection fraction (HFpEF) and HF with reduced ejection fraction (HFrEF) subgroups.

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Lower gastrointestinal bleeding (LGIB) is associated with significant morbidity and mortality in the elderly population. Timely diagnosis and establishing the etiology of the LGIB can guide appropriate treatment and management. Our patient is a 91-year-old female who presented to the ER with the complaint of several episodes of hematochezia that started four hours before her presentation.

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Uremic pericardial effusion and pericarditis in end-stage kidney disease patients remain one of the causes responsible for high rates of morbidity and occasional mortality. While clinical presentation could be variable, clinicians should have a high index of suspicion for uremic pericarditis especially in patients who miss their dialysis sessions. We present a 77-year-old man with end-stage renal disease on dialysis diagnosed with pericarditis and large pericardial effusion complicated by cardiac tamponade and shock.

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Ultrasound elastography is gaining attention for its diagnostic potential across various medical fields, and its physical properties make it valuable in modern clinical medicine. However, its specific attributes, especially in the context of recent medical advancements, remain relatively unexplored. This study aimed to identify instrument-specific characteristics and applications of real-time ultrasound elastography, shear wave elastography, and strain elastography, particularly within gastroenterology.

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Prostate cancer, a common malignancy in males, can metastasize to various sites such as the bone, brain, liver, and less commonly, the lung. Detecting pulmonary metastases presents both diagnostic and therapeutic difficulties. Identifying patients with this condition is crucial for gaining a deeper comprehension of the disease's pathogenesis.

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Calcium channel blockers are a major cause of cardiovascular toxicity. The clinical spectrum of these patients is very variable and there is no consensus on the dose required for toxicity. We present a case of a 43-year-old transgender woman who presented with hypotension and tachycardia owing to drug overdose that was later confirmed to be amlodipine.

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Sickle cell disease (SCD) is a prevalent inherited blood disorder with various ocular manifestations, including sickle cell retinopathy (SCR), characterized by retinal microcirculation impairment and ischemic complications. We present the case of a 21-year-old male with sickle cell trait who experienced a sudden, painless loss of vision in his left eye. Ophthalmologic examination revealed vitreous hemorrhage and neovascularization, indicating SCR.

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