Publications by authors named "Nishu Choudhary"

Article Synopsis
  • Scientists created a new mouse model to study alcohol-associated hepatitis (AAH) that is more similar to humans than older models.
  • They fed male mice a special diet containing alcohol and a chemical called thioacetamide for 12 weeks to induce liver damage.
  • The results showed that these mice had major signs of liver problems, inflammation, and changes in gut bacteria, making it a better tool to study AAH compared to other methods.
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The environmental monitoring and remediation of highly toxic inorganic arsenic species in natural water are needed for the benefit of the ecosystem. Current studies on arsenic detection and removal often employ separate materials, which exhibit blue luminescence with fluorescence quenching, making them unsuitable for biological and environmental samples. In this study, carbon dot-embedded mesoporous silica tubes functionalized with melamine are synthesized to address these limitations and enable specific and turn-on probing of inorganic arsenic.

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Environmental remediation with a single platform for selective sensing and removal of toxic analytes with recyclability of the material has always been a desirable system for sustainability. However, materials comprising all the abovementioned advantages are rarely known for oxoanions. We herein developed a fluorogenic napthalimide-based functionalized mesoporous silica material (SiO@NBDBIA) as a signaling and remediation system for oxoanions (CrO, CrO, and MnO) from a pool of several anions.

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Background: Anticholinergic drugs are associated with significant cognitive and other adverse events in older adults, including those with Parkinson's disease (PD). Anticholinergic effects are considered lesser in younger individuals and the burden and outcomes in younger patients with PD are unknown.

Objectives: To determine the cumulative anticholinergic burden in a cohort of younger of patients with PD and to correlate the same with cognitive impairment and freezing of gait (FOG).

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