Differential expression of cellular prion protein (PrP) in mouse hepatitis virus induced neuroinflammation.

The cellular prion protein (PrP) is an extracellular cell membrane protein. Due to its diversified roles, a definite role of PrP has been difficult to establish. During viral infection, PrP has been reported to play a pleiotropic role.

Mechanisms underlying microglial colonization of developing neural retina in zebrafish.

Microglia are brain-resident macrophages that function as the first line of defense in brain. Embryonic microglial precursors originate in peripheral mesoderm and migrate into the brain during development. However, the mechanism by which they colonize the brain is incompletely understood.