Publications by authors named "Nishtha Nayyar"

Diamondback moth, Plutella xylostella is a serious pest of cruciferous vegetables and causes substantial economic loss all over the world. This study was undertaken to decipher the molecular mechanisms involved in the field evolved insecticide resistance in P. xylostella upon exposure to spinosad.

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System level knowledge of alterations in host is crucial to elucidate the molecular events of viral pathogenesis and to develop strategies to block viral establishment and amplification. Here, we applied quantitative proteomics approach to study global proteome changes in the host; Spodoptera frugiperda upon infection by a baculovirus, Spodoptera litura NPV at two stages i.e.

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Brain regeneration in planarians is mediated by precise spatiotemporal control of gene expression and is crucial for multiple aspects of neurogenesis. However, the mechanisms underpinning the gene regulation essential for brain regeneration are largely unknown. Here, we investigated the role of the family of microRNAs in planarian brain regeneration.

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Article Synopsis
  • M. tuberculosis H37Rv can enter a dormant state to survive host-induced stress, with toxin-antitoxin (TA) systems playing a key role in this process.
  • The study focused on the parDE2 operon, which encodes a toxin (MParE2) and an antitoxin (MParD2), and found that MParD2 regulates its own promoter and neutralizes the toxic effects of MParE2.
  • The expression of MParE2 inhibits the growth of bacterial cells, leading to a viable but non-culturable state, indicating its potential involvement in dormancy and adaptation to stress, paving the way for further research on its role in mycobacterial pathogenesis.
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