A randomized study of the safety and efficacy of fondaparinux versus placebo in the prevention of venous thromboembolism after coronary artery bypass graft surgery.

Unlabelled: Venous thromboembolism (VTE) after coronary artery bypass graft (CABG) surgery may increase the postoperative morbidity and mortality. Therefore, we examined the current postoperative need for prophylactic antithrombotic therapy after CABG surgery.

Methods: This randomized, placebo-controlled, double-blind study was designed to compare the safety and efficacy of fondaparinux versus placebo in the prevention of VTE after CABG surgery.

Left atrial appendage filling defects on 64-slice multidetector computed tomography in patients undergoing pulmonary vein isolation: predictors and comparison to transesophageal echocardiography.

Objectives: To evaluate predictor variables and accuracy of left atrial appendage (LAA) filling defects seen on multidetector computed tomographic (MDCT) scan in predicting LAA thrombus in patients undergoing pulmonary vein (PV) isolation procedure.

Methods: Electrocardiogram-gated 64-slice MDCT and transesophageal echocardiography (TEE) were undertaken in 51 consecutive patients with nonvalvular atrial fibrillation who were referred for circumferential antral pulmonary vein isolation.

Results: In 51 patients (37 men; mean age, 64 years), left atrium (LA) diameter emerged as the predictor of LAA filling defects (odds ratio, 4.

Embryonal prostatic rhabdomyosarcomas disguised presentation in an adolescent male: a case report.

Primary rhabdomyosarcoma of the prostate is a malignancy primarily of pediatric age group with most cases seen during infancy and childhood. Majority present with urinary symptoms but the case we report here presented at 16 years of age and had unusually nonspecific and temporally protracted nature of symptoms prior to the presentation. This remarkable unusualness lead to a delay in presentation and contributed to an eventually unfavorable outcome.

Fluoroscopic coronary calcification and exercise stress test in asymptomatic elderly Asian-Indians.

Objective: Provide preliminary data on prevalence and functional significance (association with atherosclerotic risk factors and stress test positivity) of fluoroscopically detected CAC (Coronary Artery Calcification) in asymptomatic elderly Indian-Asian.

Design: Prospective observational study.

Setting: Outpatient services at 1000-bed tertiary care hospital in Northern India.

Stress cardiomyopathy: clinical and ventriculographic characteristics in 107 North American subjects.

Background: Stress cardiomyopathy (SCM) is a newly described reversible cardiomyopathy of largely unclear etiology. We studied SCM in a large cohort to gain further insights.

Methods: We retrospectively identified 114 cases of SCM from among 12,150 consecutive North American patients diagnosed as Troponin-positive acute coronary syndrome, from January 2000 through December 2007, at two 24-h coronary angioplasty-capable centers.

Dysgeusia in symptomatic syndrome of inappropriate antidiuretic hormone secretion: think of lung cancer.

The case of a 60-year-old woman who presented with marked dysgeusia to all food and symptomatic syndrome of inappropriate antidiuretic hormone secretion (SIADH) is described. She eventually turned out to have metastatic small cell lung cancer. The case study explores the interesting constellation of dysgeusia, SIADH and lung cancer.