Surgical Management and Outcome of Open Globe Injuries with Posterior Segment Complications: A 10-Year Review.

Purpose: To describe the characteristics, management, and outcomes of open globe injured (OGI) eyes that underwent pars plana vitrectomy (PPV) for posterior segment complications.

Methods: Retrospective chart review of cases that underwent PPV for posterior segment complications associated with OGI between 2003-2012 at University Hospital, Newark, NJ.

Results: 120 eyes were identified and classified as follows: "early retinal detachment (RD)" (within 30 days of OGI), 64 (53%) eyes; "delayed RD" (≥30 days after OGI), 30 (25%) eyes; and "no RD," 26 (22%) eyes.

Preservation of the Corneal Epithelium in Different Corneal Storage Media.

Purpose: With increasing time, epithelial defects (EDs) develop in virtually all corneas stored in corneal storage media. Optisol GS and Life 4°C are commonly available intermediate storage media used for corneal storage before keratoplasty. Epithelial preservation capabilities of Life 4°C and Optisol GS are compared in this study.

Blood-derived topical therapy for ocular surface diseases.

Human serum-derived and plasma-derived therapies have become increasingly popular in the treatment of ocular surface disorders, with mounting clinical and scientific evidence suggesting good safety and efficacy profiles. These therapies may be considered for various ocular surface conditions, such as dry eye syndrome and persistent epithelial defect, when conservative management does not suffice. The costly and inconvenient process of obtaining the blood-derived products is the barrier to their more widespread use.

Open globe ocular trauma: functional outcome of eyes with no light perception at initial presentation.

Purpose: To evaluate characteristics and prognostic factors for functional success in eyes that present with no light perception (NLP) after open globe trauma.

Methods: The medical records of all subjects presenting to a single university referral center with visual acuity (VA) of NLP after sustaining an open globe eye injury from January 1, 2001, through June 30, 2010, were retrospectively analyzed to determine epidemiologic and clinical factors associated with visual outcomes.

Results: Of the 73 NLP eyes (73 patients) that underwent primary repair and were included in the study, final VA was 20/100 in 1 eye (1%), counting fingers in 2 eyes (3%), hand motion in 9 eyes (12%), light perception in 5 eyes (7%), and NLP in 56 eyes (77%).