Publications by authors named "Nisang Chen"

Article Synopsis
  • - The study investigates the effectiveness of intradermal acupuncture (IA) as an alternative therapy for major depressive disorder (MDD) in a trial involving 120 participants, comparing it with selective serotonin reuptake inhibitors (SSRIs) and sham acupuncture.
  • - After 6 weeks of treatment, the group receiving SSRIs combined with active IA showed significantly greater improvement in depression scores than those on SSRIs alone or SSRIs with sham acupuncture, with no serious side effects reported.
  • - MRI analyses indicated that IA treatment improved functional connectivity in the brain regions associated with mood regulation, suggesting its potential role as an effective adjunct therapy for MDD.
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Objective: To observe the alteration of thoracic and lumbar physiological curvature in adolescent idiopathic scoliosis(AIS) and the difference of physiological curvature between different types of scoliosis.

Methods: A retrospective analysis was conducted on 305 adolescent patients taken full spine X-ray in our hospital from January 2017 to December 2021. The patients were divided into normal group and scoliosis group.

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Article Synopsis
  • * The study will involve 60 participants (20 healthy controls and 40 MDD patients) who will receive a one-time IA intervention while their cortical activity is tracked using functional near-infrared spectroscopy (fNIRS) to measure changes in blood flow in the relevant brain regions.
  • * The goal of the trial is to determine if MDD patients respond differently in real-time to IA in their prefrontal and temporal cort
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Background: Major depressive disorder (MDD) exhibits a pronounced occurrence among adolescents, aligning closely with the lifetime prevalence rate of 16.6% observed in adults. It is difficult to treat and prone to recurrence.

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Background: Antidepressants still have some side effects in treating major depressive disorder (MDD), and acupuncture therapy is a complementary therapy of research interest for MDD. Acupoints are sensitive sites for disease response and stimulation points for acupuncture treatment. Prior studies suggest that the biological specificity of acupoints is altered in physiological and pathological situations.

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Background: Major depressive disorder (MDD) has emerged as the fifth leading cause of years lived with disability, with a high prevalent, affecting nearly 4% of the global population. While available evidence suggests that intradermal acupuncture may enhance the effectiveness of antidepressants, whether its efficacy is a specific therapeutic effect or a placebo effect has not been reported. Moreover, the cerebral mechanism of intradermal acupuncture as a superficial acupuncture (usually subcutaneous needling to a depth of 1-2 mm) for MDD remains unclear.

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