Function of AP2/ERF Transcription Factors Involved in the Regulation of Specialized Metabolism in Revealed by Transcriptomics and Metabolomics.

The hairy roots (HR) of produce camptothecin (CPT), a monoterpenoid indole alkaloid used as a precursor in the synthesis of chemotherapeutic drugs. HR culture is considered as a promising alternative source of CPT, however, the knowledge about the biosynthetic pathway and regulatory mechanism is still limited. In this study, five genes that encode AP2/ERF transcription factors, namely -, were isolated from HR of .