Publications by authors named "Nirav V Shah"
Ophthalmologic Findings in Pediatric Erdheim-Chester Disease: A Literature Review With a Novel Case Report.
Ophthalmic Plast Reconstr Surg
February 2024
Article Synopsis
- The study focuses on the eye-related symptoms of Erdheim-Chester disease (ECD) in children, highlighting a new case with isolated bilateral proptosis.
- A total of 20 pediatric cases were analyzed, revealing that nearly half had eye involvement, with common symptoms including proptosis and diplopia.
- The findings suggest that isolated eye symptoms can be the only indicator of ECD, emphasizing the need for ophthalmologists to consider this diagnosis when encountering cases of bilateral exophthalmos in children.
Conjunctival melanoma is a rare tumor of the conjunctival epithelium with a heterogenous clinical presentation and a propensity for regional and distant metastatic spread. Guidelines for the treatment of local conjunctival melanoma are well-established, but there are no standard efficacious therapies for metastatic disease. Given that conjunctival melanoma is genetically similar to cutaneous melanoma and mucosal melanomas, targeted therapies effective in the treatment of these diseases, such as BRAF inhibitors and KIT inhibitors, may be effective in the treatment of patients with metastatic conjunctival melanoma.
View Article and Find Full Text PDFBackground: Several malignancies metastasize to the adrenal gland, especially non-small cell lung cancer, renal cell carcinoma, and melanoma. Adrenalectomy is associated with prolonged survival, but laparoscopic adrenalectomy for this indication is controversial. Our objective was to characterize and quantify outcomes after laparoscopic adrenalectomy for metastases to the adrenal gland.
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