Publications by authors named "Nirav Asarawala"

Cancer clinical trials are instrumental in driving forward medical advancements and enhancing patient outcomes. However, despite their significance, only a small fraction of adult cancer patients, less than one in 20, participate in these trials, indicating significant obstacles in recruitment and engagement. These trials not only assess treatment effectiveness but also serve as vibrant platforms where scientific ingenuity converges with human resilience, fostering a culture of exploration and empowerment.

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This case report outlines the diagnostic and treatment experience of a 50-year-old male diagnosed with moderately differentiated squamous cell carcinoma (SCC) in the right lower alveolus. It underscores the challenges of oral squamous cell carcinoma (OSCC) diagnosis and management, emphasizing the need for comprehensive multidisciplinary approaches. The patient's initial presentation with persistent mandibular pain highlighted the complexities of diagnosing oral and maxillofacial pathologies.

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Importance: Locoregionally advanced head and neck squamous cell cancer (HNSCC) is treated curatively; however, risk of recurrence remains high among some patients. The ERBB family blocker afatinib has shown efficacy in recurrent or metastatic HNSCC.

Objective: To assess whether afatinib therapy after definitive chemoradiotherapy (CRT) improves disease-free survival (DFS) in patients with HNSCC.

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