Publications by authors named "Nir Y Uriel"
Background: Prior analyses have suggested that a smaller left ventricular end-diastolic diameter (LVEDD) is associated with reduced survival following HeartMate 3 left ventricular assist device implantation.
Objectives: In this trial-based comprehensive analysis, the authors sought to examine clinical characteristics and association with the outcome of this specific relationship.
Methods: The authors analyzed the presence of LVEDD <55 mm among 1,921 analyzable HeartMate 3 patients within the MOMENTUM 3 (Multicenter Study of MagLev Technology in Patients Undergoing Mechanical Circulatory Support Therapy With HeartMate 3) trial portfolio, on endpoints of overall survival and adverse events at 2 years.
Article Synopsis
- The study looked at how to manage blood thinners after people got a special heart device called HeartMate 3.
- It compared two methods for checking the right dose of a blood thinner called unfractionated heparin (UFH).
- There were no big differences in bleeding or clotting problems between the two methods, but more research is needed to know which one is better.
Article Synopsis
- The study aimed to compare outcomes of younger (18-65 years) and older (over 65 years) patients who received simultaneous heart-kidney (SHK) transplants, analyzing data from 1398 recipients.
- Results showed that both age groups had similar baseline characteristics and that older patients did not experience higher mortality rates after transplantation, with 90-day survival rates at 85% and 7-year survival rates at 61% for both cohorts.
- The findings suggest that age and functional dependence should not be the sole criteria for excluding older patients from receiving SHK transplants; instead, a comprehensive assessment of their overall health and comorbidities is necessary.
Biventricular Pacing Versus Right Ventricular Pacing in Patients Supported With LVAD.
JACC Clin Electrophysiol
August 2021
Objectives: This study sought to evaluate the effects of right ventricular (RV) pacing versus biventricular (BiV) pacing on quality of life, functional status, and arrhythmias in LVAD patients.
Background: Cardiac resynchronization therapy (CRT) and left ventricular assist devices (LVADs) independently improve outcomes in heart failure patients, but the effects of combining these therapies remains unknown. We present the first prospective randomized study evaluating the effects of RV versus BiV pacing on quality of life, functional status, and arrhythmias in LVAD patients.