Publications by authors named "Ninna M Koho"
Article Synopsis
- Increased cases of bacterial pneumonia (BP) have been noted in Irish Wolfhounds (IWHs), particularly among middle-aged and older dogs, with a median of 5 previous BP episodes reported.
- A study involving 11 affected IWHs, along with healthy control groups, examined various clinical aspects and potential causes of the recurrent BP, such as bronchiectasis and laryngeal paralysis.
- No significant immune deficiencies or ciliary defects were found, suggesting that structural issues in the respiratory system, specifically focal bronchiectasis, along with some laryngeal and esophageal dysfunction, likely contribute to the recurrent infections.
OBJECTIVE To examine whether expression of extracellular matrix metalloproteinase inducer (EMMPRIN) can be detected in equine lungs and whether it correlates with matrix metalloproteinase (MMP)-2 and -9 expression in bronchoalveolar lavage fluid (BALF) of horses with chronic inflammation of the lungs (ie, lower airway inflammation [LAI]). ANIMALS 29 horses with signs of chronic respiratory tract disease, which were classified as the LAI (n = 17) and LAI with respiratory distress (RDLAI [12]) groups, and 15 control horses. PROCEDURES BALF, tracheal aspirate, and blood samples were obtained, and EMMPRIN expression was determined from BALF cells and RBCs by use of western blotting.
View Article and Find Full Text PDFObjective: To characterize the expression of monocarboxylate transporters (MCTs) 1 and 4 and the ancillary protein CD147 in the intestinal tract of healthy equids and determine the cellular location of CD147 in the intestinal epithelium.
Animals: 12 healthy horses and ponies slaughtered for meat production or euthanized for reasons unrelated to gastrointestinal tract disease.
Procedures: The entire gastrointestinal tract was removed from each equid within 45 minutes after slaughter or euthanasia.
The reason why some horses begin an oral stereotypy such as crib-biting is not known. The aim of this study was to measure ghrelin and leptin concentrations in plasma concentrations to determine whether there is a link to crib-biting in horses. Plasma samples (n=3) were collected for plasma leptin and ghrelin assay before and during the morning first feeding in the usual environments of 15 horses with stereotypic crib-biting and 15 matched controls.
View Article and Find Full Text PDFA prospective observational study was performed to evaluate whether the plasma concentration of heat shock protein 72 (HSP72) or beta-endorphin is related to clinical signs, blood chemistry, or severity of pain of colic. Seventy-seven horses with colic and 15 clinically healthy controls were studied. The horses were divided into four groups which reflected increasing severity of colic, from normal control horses to horses with mild, moderate and severe colic.
View Article and Find Full Text PDFObjective: To detect monocarboxylate transporters (MCTs) in canine RBC membranes and to determine the distribution of lactate between plasma and RBCs.
Sample Population: Blood samples obtained from 6 purpose-bred Beagles.
Procedures: Monocarboxylate transporter isoforms 1, 2, 4, 6, 7, and 8 and CD147 were evaluated in canine RBCs by use of western blot analysis.