Publications by authors named "Ningxin Guo"
Article Synopsis
- Bacterial septicemia from Aeromonas hydrophila is a significant issue in aquaculture, and this study focuses on how hepcidin, an antimicrobial peptide, helps defend mandarin fish against this pathogen.
- The research analyzed the expression of genes related to iron metabolism and immune response in the fish’s intestine after infection, revealing peak expression times for various genes and changes in iron levels.
- Findings indicate that hepcidin initially limits bacterial growth by regulating iron levels and later modulates immune responses, highlighting its potential role in managing bacterial infections in fish farming.
An acetic acid-promoted approach that enables the synthesis of 1,4,5-trisubstituted 1,2,3-triazole derivatives has been achieved. This transformation employs readily available primary amines, 1,3-dicarbonyls and tosyl azide as the starting materials via a cycloaddition reaction under metal-free conditions. The reaction provides a simple access to fully substituted 1,2,3-triazoles from commercial substrates in moderate to excellent yields.
View Article and Find Full Text PDFRh(III)-catalyzed C(sp)-H bond aminocarbonylation of 8-methylquinolines and isocyanates has been realized under mild conditions. This approach is applicable to different aryl and alkyl isocyanates, leading to the synthesis of various α-quinolinyl amide compounds in moderate to excellent yields. A plausible mechanism for this transformation is proposed according to the experimental results obtained.
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