Publications by authors named "Ningxin Dou"
Objectives: To propose and evaluate a novel, non-invasive approach for enduring corneal astigmatism correction based on topography-guided, patterned, customized riboflavin-ultraviolet A corneal collagen crosslinking (CXL).
Methods: Astigmatism was modelled on both eyes of rabbits. A randomly selected eye of each rabbit was treated by the proposed CXL procedure with another eye as control.
Article Synopsis
- - The study aimed to analyze how the Omicron variant affected the incidence and clinical presentation of acute primary angle closure (APAC) in patients at Shenzhen Eye Hospital during the pandemic.
- - Compared to two pre-pandemic control periods, the prevalence of APAC was significantly higher during the Omicron outbreak, with a rise from 7.87% and 8.96% in control groups to 23.43% in the pandemic cohort, along with increased surgical rates and larger pupil diameters among patients.
- - Key findings revealed that 83% of Omicron-infected patients experienced ocular symptoms within three days of systemic symptoms, suggesting a potential link between Omicron infection and increased severity of APAC during this period.
Association between choroidopathy and photoreceptors during the early stage of diabetic retinopathy: a cross-sectional study.
Graefes Arch Clin Exp Ophthalmol
April 2024
Purpose: To explore the role of choroidopathy in diabetic retinopathy (DR) by investigating the correlation between alterations of choroidal vessel and photoreceptors during the early stage of DR.
Methods: We performed a cross-sectional comparison of diabetic patients without DR (NDR group; n=16) and those with mild nonproliferative diabetic retinopathy (NPDR group; n=39). Optical coherence tomography (OCT) images of choroidal vessel alterations and photoreceptor structures were evaluated using the choroidal vascularity index (CVI) and adjusted ellipsoid zone (EZ) reflectivity, respectively.
Purpose: To investigate the choroidal vascularity index (CVI) as a prognostic factor for the visual efficacy of antivascular endothelial growth factor (VEGF) treatment in diabetic macular edema (DME).
Methods: We retrospectively reviewed 92 DME eyes receiving anti-VEGF treatment, which were stratified as responders (≥5 letters gained) and nonresponders (<5 letters gained or lost). Baseline systematic features and optical coherence tomography features, including the CVI, adjusted ellipsoid zone (EZ) reflectivity, subretinal fluid (SRF), and disorganization of the retinal inner layers (DRIL), were evaluated between the two groups.