Publications by authors named "Ninglei Qiu"

Background: Tracheo-carinal resection and reconstruction in cases of extensive malignant tumors present a significant surgical challenge, often complicated by high anastomotic tension and potential for incomplete anastomosis.

Case Description: We report on a 45-year-old male with a primary adenoid cystic carcinoma. The tumor was about 3 cm in size and invaded about 1 cm of the lower trachea, 2 cm of the left main bronchus (LMB), and 1 cm of the right main bronchus (RMB), blocking about 70% of the tracheal lumen, 90% of the LMB, and 50% of the RMB.

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Background: Bilateral multiple ground glass opacities (GGOs) are observed in quite a part of patients with early-stage lung adenocarcinoma. For this so-called synchronous multiple primary lung cancer (sMPLC), targeting immune checkpoint is a favorable option in addition to surgical resection. The purpose of this study is to reveal the safety and efficacy of performing immune checkpoint inhibitors (ICIs) on patients with sMPLC and to explore the biomarkers of the efficacy.

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Article Synopsis
  • Circulating tumor DNA (ctDNA) is a promising biomarker for monitoring minimal residual disease (MRD) in non-small-cell lung cancer (NSCLC), particularly in patients who underwent surgery.
  • A study involving 128 patients showed that ctDNA detection is more common in those with advanced disease and that positive ctDNA results shortly after surgery can identify patients at high risk for recurrence.
  • Long-term monitoring of ctDNA revealed that recurring cancer symptoms could appear significantly earlier than traditional imaging methods, suggesting the potential to tailor follow-up care based on ctDNA findings.
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Background: Carinal resection and reconstruction is an emphasis in surgical treatment of carinal tumor and bronchogenic carcinoma involving carina. The aim of this study is to discuss the clinical value of carinoplasty in lung cancer surgery.

Methods: From 1982 to 2004, 41 cases of central bronchogenic carcinoma that invaded the carina accepted carinal resection and reconstruction in this hospital.

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Background: To summarize the surgical treatment for locally advanced lung cancer invading heart and great vessels.

Methods: One hundred and eighteen cases of lung cancer accepting cardiovascular plasty operation from 1980 to 2001 were reviewed.

Results: The operations included partial resection of left atrium in 38 cases, pulmonary artery resection and restruction in 48 cases, replacement or partial resection of superior vena cava in 25 cases, partial resection of pulmonary conus in 3 cases, and lober replantation in 4 cases respectively.

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