Quantitative structure-chromatographic retention relationship of synthesized peptides (HGRFG, NPNPT) and their derivatives.

Carapax Trionycis extract peptides (HGRFG, NPNPT) are able to protect against CCl-induced liver fibrosis. Therefore, this study applies to deal with chromatographic lipophilicity determination of synthesized peptides (HGRFG, NPNPT) and their derivatives using reversed-phase high performance liquid chromatography (RP-HPLC) combined with methanol-water mobile phase and two reversed-phase chromatographic columns (COSMOISL 5C18-MS-II and SHIMADZU-C18). The chromatographic lipophilicity of the analyzed compounds was expressed as logk constant and correlated with lipophilicity descriptors.

A Highly Selective and Sensitive Colorimetric Probe for Cu Determination in Aqueous Media Based on Derivative of Tryptanthrin.

A new colorimetric probe, based on tryptanthrin derivative (TR-A), has been successfully synthesized. The probe shows good selectivity and sensitivity for Cu over 12 competing metal ions in a 10 mM Tris-HCl buffer solution (pH 5.5).