Behavior of a Precast Bridge Pier with Basalt Fiber-Reinforced Polymer (BFRP)-Strengthened Segments under Seismic Loading.

The precast segmental column (PSC) has been proposed for reducing onsite construction time and minimizing impacts on traffic and the environment. It has been proven to have good seismic performance according to previous studies. However, due to the rocking behavior of the column, the toe of the bottom segment could experience excessive compressive damage.

Accumulation and growth toxicity mechanisms of fluxapyroxad revealed by physiological, hepatopancreas transcriptome, and gut microbiome analysis in Pacific white shrimp (Litopenaeus vannamei).

Fluxapyroxad (FX), a typical succinate dehydrogenase inhibitor fungicide, is causing increased global concerns due to its fungicide effects. However, the accumulation and grow toxicity of FX to Litopenaeus vannamei (L. vannamei) is poorly understand.

Super-resolution terahertz synthetic aperture image reconstruction algorithm.

The resolution of terahertz images based on the near-field synthetic aperture radar (NSAR) imaging mode is low due to the narrow antenna beamwidth and the electromagnetic wave loss that was ignored by previous algorithms. We propose a super-resolution terahertz NSAR imaging algorithm. There are two algorithm steps: First, we use the forward mathematical model of the NSAR imaging system and the back-projection algorithm (BPA) to calculate the point spread function (PSF).

Accumulation and elimination properties and comparative toxicity of fluxapyroxad in juvenile and adult large yellow croaker (Larimichthys crocea).

Fluxapyroxad (FX), a succinate dehydrogenase inhibitor fungicide, has been detected in global marine and aquatic organisms. However, as a new pollutant, its biotoxicity and ecological risks to marine aquatic organisms are unclear. The accumulation and elimination processes and toxic effects of FX on Larimichthys crocea (L.

Research progress of glucocorticoid resistance in chronic rhinosinusitis with nasal polyps: A review.

Chronic rhinosinusitis with nasal polyps (CRSwNP) is one of the common chronic inflammatory diseases in otolaryngology. Glucocorticoid (GC) acts as the first-line drug for the treatment of CRSwNP in clinical practice, and they play an irreplaceable role in reducing nasal mucosal inflammation and restoring the normal physiological function of the nasal mucosa. However, many patients are still insensitive to GC treatment, known as GC resistance, which leads to poor control of the disease, and the underlying mechanisms are still not fully elucidated.

Terahertz 3D point cloud imaging for complex targets.

The reconstruction of complex targets using terahertz technology is often hindered by diffraction and interference of electromagnetic waves, leading to the loss of fine target details. In this research article, we have introduced a terahertz synthetic aperture radar (SAR) imaging method that integrates an iterative closest point (ICP) algorithm, referred to as SAR-ICP, to achieve accurate reconstruction of intricate target structures. To accomplish this, multiple sets of point cloud data are acquired by varying the illumination viewpoint.

Klobuchar, NeQuickG, BDGIM, GLONASS, IRI-2016, IRI-2012, IRI-Plas, NeQuick2, and GEMTEC Ionospheric Models: A Comparison in Total Electron Content and Positioning Domains.

Global navigation satellite systems (GNSS) provide a great data source about the ionosphere state. These data can be used for testing ionosphere models. We studied the performance of nine ionospheric models (Klobuchar, NeQuickG, BDGIM, GLONASS, IRI-2016, IRI-2012, IRI-Plas, NeQuick2, and GEMTEC) both in the total electron content (TEC) domain-i.

Rose essential oil diminishes dopaminergic neuron degenerations and reduces α-synuclein aggregation in Caenorhabditis elegans models of Parkinson's disease.

Parkinson's disease (P.D.) is the second most progressive neurodegenerative disorder in the elderly.

Transcriptome sequencing and metabolite analysis reveal the single and combined effects of microplastics and di-(2-ethylhexyl) phthalate on Peneaus vannamei.

Due to the rising usage of plastics, plastic debris are present throughout marine ecosystems and detrimentally affects marine biota. Additionally, plastics likely result in elusive toxicity effects due to addition of plasticizers. The aim of the present study was to reveal the potential effects and mechanism of microplastics (MPs), di-(2-ethylhexyl) phthalate (DEHP) and copollution of MPs and DEHP (MPs-DEHP) on Peneaus vannamei (P.

Neuroprotective effects of cannabidiol on dopaminergic neurodegeneration and α-synuclein accumulation in C. elegans models of Parkinson's disease.

Parkinson disease (PD) is the second most progressive neurodegenerative disorder of the central nervous system (CNS) in the elderly, causing motor impediments and cognitive dysfunctions. Dopaminergic (DA) neuron degeneration and α-synuclein (α-Syn) accumulation in substantia nigra pars compacta (SNPc) are the major contributor to this disease. At present, the disease has no effective treatment.

Black mulberry (Morus nigra) fruit extract alleviated AD-Like symptoms induced by toxic Aβ protein in transgenic Caenorhabditis elegans via insulin DAF-16 signaling pathway.

Alzheimer's disease (AD) is one of the most severe neurodegenerative disorders. Recently, there is no effective treatment drug for AD. Morus nigra (M.

Juvenile hormone promotes paracellular transport of yolk proteins via remodeling zonula adherens at tricellular junctions in the follicular epithelium.

Juvenile hormone (JH) acts as a gonadotrophic hormone stimulating insect vitellogenesis and oogenesis. Paracellular transport of yolk proteins through intercellular channels (patency) in the follicular epithelium is a developmentally regulated and evolutionarily conserved process during vitellogenesis. However, the mechanisms underlying patency opening are poorly understood.

A Novel Elastomer-Based Inclinometer for Ultrasensitive Bridge Rotation Measurement.

Bridge deformation consists of cross-section rotation and deflection, which are crucial parameters for bridge capacity evaluation and damage detection. The maximum value of deflection usually happens at mid-span while for rotation it happens at two-ends. Therefore, compared with deflection, rotation is more convenient for in-situ measurement since the bridge pier can be the reference point.

Anti-α-synuclein Toxicity and Anti-neurodegenerative Role of Chrysin in Transgenic Models of Parkinson's Disease.

Parkinson's disease (PD) is the second most progressive neurodegenerative disorder of the central nervous system in the elderly, causing motor impediments and cognitive dysfunctions. Dopaminergic (DA) neuron degeneration and α-synuclein (α-Syn) accumulation in substantia nigra pars compacta are the major contributors to this disease. At present, PD remains untreatable with a huge burden on the quality of life.

Ursolic acid ameliorates amyloid β-induced pathological symptoms in Caenorhabditis elegans by activating the proteasome.

Background: Amyloid β induces pathological symptoms in various neurodegenerative disorders. It is the hallmark of these neurodegenerative disorders, such as Alzheimer's disease, and is reported to induce neurotoxicity leading to neuronal impairment. The continuous development of neurodegenerative disease accompanies pathological changes in amyloid β deposition in the brain.

LncRNA TUG1 acts as a competing endogenous RNA to mediate CTGF expression by sponging miR-133b in myocardial fibrosis after myocardial infarction.

Myocardial fibrosis (MF) is one of the basic causes of many cardiovascular diseases. Noncoding RNAs (ncRNAs), including microRNA (miRNA) and long noncoding RNA (lncRNA), have been reported to play an indispensable role in MF. The current work is focused on investigating the biological role of lncRNA taurine upregulation gene 1 (TUG1) in activating cardiac myofibroblasts as well as the underlying mechanism.

Sub-Auroral and Mid-Latitude GNSS ROTI Performance during Solar Cycle 24 Geomagnetic Disturbed Periods: Towards Storm's Early Sensing.

Geomagnetic storms-triggered by the interaction between Earth's magnetosphere and interplanetary magnetic field, driven by solar activity-are important for many Earth-bound aspects of life. Serious events may impact the electroenergetic infrastructure, but even weaker storms generate noticeable irregularities in the density of ionospheric plasma. Ionosphere electron density gradients interact with electromagnetic radiation in the radiofrequency domain, affecting sub- and trans-ionospheric transmissions.

Comparative study on intercalation-exfoliation and thermal activation modified kaolin for heavy metals immobilization during high-organic solid waste pyrolysis.

With the new municipal solid waste classification policy implemented in China, attention on achieving the waste-to-energy disposal of "dry waste" has been growing. Pyrolysis conversion of organic waste into value-added chemicals is a promising method to treat solid waste. However, after removing the non-combustible components of "dry waste", the obtained high-organic solid waste (HSW) contains various heavy metals, which requires urgent attention during thermochemical conversion.

Theoretical study on the adsorption mechanism of PbCl/CdCl by kaolinite during municipal solid waste pyrolysis.

In the process of municipal solid waste (MSW) pyrolysis, kaolinite possesses an outstanding trapping effect on semi-volatile metal vapors (Pb, Cd) through physical and chemical adsorption. In this paper, the microscopic mechanism of PbCl and CdCl adsorption on the surface of Al rings and Si rings of kaolinite was investigated by combining Monte Carlo method with density functional theory (DFT). The calculations indicate that the continuously enriched pore structure in the process of dehydroxylation indirectly influences the adsorption of PbCl/CdCl by kaolinite.

Ferulic acid delayed amyloid β-induced pathological symptoms by autophagy pathway via a fasting-like effect in Caenorhabditis elegans.

The amyloid β (Aβ) generation or aggregation plays a crucial role in Alzheimer's disease (AD). Autophagy agonists, which function as the clearance of Aβ, could be the potential drug candidates against AD. In staple food crops, ferulic acid (FA) is an enormously copious and almost ubiquitous phenolic antioxidant.

A Multi-Sensor Tight Fusion Method Designed for Vehicle Navigation.

Using the Global Navigation Satellite System (GNSS), it is difficult to provide continuous and reliable position service for vehicle navigation in complex urban environments, due to the natural vulnerability of the GNSS signal. With the rapid development of the sensor technology and the reduction in their costs, the positioning performance of GNSS is expected to be significantly improved by fusing multi-sensors. In order to improve the continuity and reliability of the vehicle navigation system, we proposed a multi-sensor tight fusion (MTF) method by combining the inertial navigation system (INS), odometer, and barometric altimeter with the GNSS technique.

Protein kinase C mediates juvenile hormone-dependent phosphorylation of Na/K-ATPase to induce ovarian follicular patency for yolk protein uptake.

In oviparous animals, vitellogenesis is prerequisite to egg production and embryonic growth after oviposition. For successful insect vitellogenesis and oogenesis, vitellogenin (Vg) synthesized in the fat body (homologue to vertebrate liver and adipose tissue) must pass through the intercellular channels, a condition known as patency in the follicular epithelium, to reach the surface of oocytes. This process is controlled by juvenile hormone (JH) in many insect species, but the underlying mechanisms remain elusive.

The First Result of Relative Positioning and Velocity Estimation Based on CAPS.

The Chinese Area Positioning System (CAPS) is a new positioning system developed by the Chinese Academy of Sciences based on the communication satellites in geosynchronous orbit. The CAPS has been regarded as a pilot system to test the new technology for the design, construction and update of the BeiDou Navigation Satellite System (BDS). The system structure of CAPS, including the space, ground control station and user segments, is almost like the traditional Global Navigation Satellite Systems (GNSSs), but with the clock on the ground, the navigation signal in C waveband, and different principles of operation.