Genome Sequence of Oxalobacter formigenes Strain SSYG-15.

Colonization of the intestine with reduces urinary oxalate excretion and lowers the risk of forming calcium oxalate kidney stones. Here, we report the genome sequence of SSYG-15, a strain isolated from a stool sample from a healthy Chinese boy.

Guar gum/ethylcellulose coated pellets for colon-specific drug delivery.

The aim of this work was to investigate guar gum/ethylcellulose mix coated pellets for potential colon-specific drug delivery. The coated pellets, containing 5-fluorouracil as a model drug, were prepared in a fluidized bed coater by spraying the aqueous/ethanol dispersion mixture of guar gum and ethylcellulose. The lag time of drug release and release rate were adjustable by changing the ratio of guar gum to ethylcellulose and coat weight gain.