Publications by authors named "Ning-Xin Zhang"
Article Synopsis
- - Cadmium (Cd) causes oxidative stress in plants, and the study focuses on the role of glutaredoxins (GRXs), specifically Arabidopsis GRX480, in helping plants tolerate Cd toxicity.
- - GRX480 mutants show increased sensitivity to Cd, with negative effects on root growth, biomass, chlorophyll levels, and photosynthesis, leading to higher Cd accumulation in the plants.
- - The research suggests GRX480 plays a vital role in balancing glutathione levels and managing reactive oxygen species, which contribute to the plant's ability to detoxify and maintain redox balance under Cd stress.
Recent research has indicated that formononetin demonstrates a potent anti-inflammatory effect in various diseases. However, its impact on sterile inflammation kidney injury, specifically acute kidney injury (AKI), remains unclear. In this study, we utilized an ischemia/reperfusion-induced AKI (IRI-AKI) mouse model and bone marrow-derived macrophages (BMDMs) to investigate the effects of formononetin on sterile inflammation of AKI and to explore the underlying mechanism.
View Article and Find Full Text PDFRecent studies have demonstrated the mouse double minute gene (MDM2), a main oncogene, as a novel and interesting therapeutic target for cancer therapy. The aim of this study was to investigate the involvement of MDM2 in antiproliferative and antimetastatic effects of resveratrol in breast cancer cells. MCF-7 cells were transfected with siRNA against MDM2 and resveratrol.
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