Publications by authors named "Ning-Xi Wang"

Article Synopsis
  • A-to-I RNA editing and mA modification are crucial RNA modifications influencing gene expression and tumor development in mammals, but their interaction in cancer needs more exploration.
  • This study reveals that the enzyme ADAR1 boosts the protein level of METTL3, promoting the growth and spread of breast cancer cells through a link with YTHDF1.
  • The research shows that both ADAR1 and METTL3 are elevated in breast cancer samples, and the presence of ADAR1 enhances METTL3, leading to changes that facilitate tumor progression.
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Article Synopsis
  • MsrB1 is an enzyme involved in converting sulfoxides back to methionine and is found to be highly expressed in colorectal cancer (CRC) tissues and cell lines.
  • MsrB1 knockdown in CRC cell lines led to decreased cell proliferation, migration, and invasion, while increasing apoptosis and altering protein levels related to cell adhesion and epithelial-mesenchymal transition.
  • The study suggests that MsrB1 influences CRC tumorigenesis through the GSK-3β/β-catenin signaling pathway, highlighting its potential as a biomarker and therapeutic target for CRC treatment.
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