Publications by authors named "Ning Xin"

Central precocious puberty (CPP) is an endocrine disease in children, characterized by rapid genital development and secondary sexual characteristics before the age of eight in girls and nine in boys. The premature activation of the hypothalamic-pituitary-gonadal axis (HPGA) limits the height of patients in adulthood and is associated with a higher risk of breast cancer. How to prevent and improve the prognosis of CPP is an important problem.

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An arc fault is a potential hazard in power systems, capable of causing serious safety accidents such as fires. Therefore, the timely detection of arc faults and implementation of circuit-breaking measures are crucial for ensuring safety, preventing fires, and maintaining the stable operation of power systems. Although existing studies have made progress in improving the accuracy of their detection, most methods have not proposed effective solutions that address the cost-sensitive problem of feature selection.

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Agile control after the release of test mass is related to the success or failure of China's space gravitational wave detection program, such as TianQin and Taiji. In the release process, the test mass's motion state is complex and susceptible to collisions with the satellite cavity. In addition, the release capture control of the test mass uses electrostatic force, which is extremely small.

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Background: Serum creatinine (Cr)- and cystatin C (CysC)-based indices have been suggested as alternative markers for sarcopenia, but their predictive value for sarcopenia risk is uncertain, which was investigated in the present study in the Chinese population with the middle and older ages.

Methods: Data from the China Health and Retirement Longitudinal Study (CHARLS) were collected in the 2011 and 2015 waves. All participants were free of sarcopenia at the baseline.

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Ferroptosis, a distinct form of non-apoptotic cell death characterized by iron dependency and lipid peroxidation, is increasingly linked to various pathological conditions in pregnancy and liver diseases. It plays a critical role throughout pregnancy, influencing processes such as embryogenesis, implantation, and the maintenance of gestation. A growing body of evidence indicates that disruptions in these processes can precipitate pregnancy-related disorders, including pre-eclampsia (PE), gestational diabetes mellitus (GDM), and intrahepatic cholestasis of pregnancy (ICP).

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Human adenoviruses (HAdVs) are highly contagious pathogens with various genotypes implicated in acute respiratory disease (ARD) and linked to fatality, especially in immunosuppressed patients, young children, and military recruits. Currently, no vaccines or specific drugs are approved for clinical use. The hosts of adenoviruses are strictly species-specific, which strongly limits the development of vaccines and drugs against HAdVs.

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Background: Associations between adverse childhood experiences (ACEs) and multimorbidity among middle-aged and older Chinese individuals have not been well documented.

Objective: We aimed to examine the associations of ACEs and different multimorbidity measures among Chinese middle-aged and older adults.

Participants And Setting: The study population included 6428 participants aged 45 years or older who were obtained from the China Health and Retirement Longitudinal Study (CHARLS).

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Article Synopsis
  • * An innovative logic circuit using gold nanocubes (AuNCs) was created, which can simultaneously detect miRNA-21 and miRNA-210 in cancer cells based on specific enzymes that are overexpressed in those cells.
  • * This detection method enhances the ability to differentiate between cancerous and normal cells, and even distinguish different types of cancer cells, providing a valuable tool for early diagnosis and treatment.
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Low-voltage arc fault detection can effectively prevent fires, electric shocks, and other accidents, reducing potential risks to human life and property. The research on arc fault circuit interrupters (AFCIs) is of great significance for both safety in production scenarios and daily living disaster prevention. Considering the diverse characteristics of loads between the normal operational state and the arc fault condition, a parallel neural network structure is proposed for arc fault recognition, which is based on a convolutional neural network (CNN) and a Transformer.

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Background: One of the significant complications associated with Lung volume reduction surgery (LVRS), which is a critical intervention for patients with advanced emphysema, is the development of postoperative air leaks. We have found that oxidized regenerated cellulose (ORC) can be used in LVRS to minimize postoperative air leaks and enhance recovery in our clinical work. This study evaluates the efficacy of a novel ORC application method in improving lung function and reducing complications in patients undergoing LVRS for emphysema.

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With economic and social development, there is a growing focus on menstrual hygiene, and traditional sanitary napkins are no longer sufficient to meet women's needs. In this study, quercetin (QC) was efficiently and uniformly ultrasonic sprayed on thermally bonded chitosan nonwovens (CS) to prepare a multifunctional surface layer of sanitary napkins (QC@CS). CS sprayed with 3 layers of QC (QC@CS) exhibits excellent mechanical properties and high antibacterial rates against Escherichia coli (99.

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Few-shot class-incremental learning (FSCIL) aims to learn new classes incrementally with a limited number of samples per class. Foundation models combined with prompt tuning showcase robust generalization and zero-shot learning (ZSL) capabilities, endowing them with potential advantages in transfer capabilities for FSCIL. However, existing prompt tuning methods excel in optimizing for stationary datasets, diverging from the inherent sequential nature in the FSCIL paradigm.

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Introduction: The prevalence of vitamin D deficiency and vitamin D levels in patients with epilepsy (PWE) were systematically evaluated, and the differences between subgroups were analyzed.

Method: We identified all articles investigating the prevalence of vitamin D deficiency in patients with epilepsy from the database established in March 2024 from PubMed, Web of Science, and Embase. We divided them into anti-seizure medication (ASM) interventions and non-ASM interventions according to whether or not someone used ASM.

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Stroke recurrence remains a critical challenge in clinical neurology, necessitating the identification of reliable predictive markers for better management and treatment strategies. This study investigates the interaction between lipoprotein-associated phospholipase A2 (Lp-PLA2) and platelets as a potential predictor for stroke recurrence, aiming to refine risk assessment and therapeutic approaches. In a retrospective cohort of 580 ischemic stroke patients, we analyzed clinical data with a focus on Lp-PLA2 and platelet levels.

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Recently, point cloud domain adaptation (DA) practices have been implemented to improve the generalization ability of deep learning models on point cloud data. However, variations across domains often result in decreased performance of models trained on different distributed data sources. Previous studies have focused on output-level domain alignment to address this challenge.

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Nanozymes, serving as synthetic alternatives to natural enzymes, offer several benefits including cost-effectiveness, enzyme-like catalytic abilities, enhanced stability, adjustable catalytic activity, easy recyclability, mild reaction conditions, and environmental friendliness. Nonetheless, the ongoing quest to develop nanozymes with enhanced activity and to delve into the catalytic mechanism remains a challenge. In our research, we effectively developed Au@CuO nanocomposites (Au@CuO Nc), replicating the functions of four enzymes found in nature: peroxidase (POD), catalase (CAT), glutathione peroxidase (GPx), and oxidase (OXD).

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Article Synopsis
  • * This study (COGITO) investigates the effectiveness of a combined exercise and cognitive training intervention in older adults with MCI using digital tools for remote monitoring and support.
  • * A total of 160 participants will be randomly assigned to one of four groups for a 3-month program, focusing on different interventions, to assess improvements in cognitive function and overall health.
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Background:  More effective methods are urgently needed for predicting the pathological grade and lymph node metastasis of cT1-stage lung adenocarcinoma.

Methods:  We analyzed the relationships between CT quantitative parameters (including three-dimensional parameters) and pathological grade and lymph node metastasis in cT1-stage lung adenocarcinoma patients of our center between January 2015 and December 2023.

Results:  A total of 343 patients were included, of which there were 233 males and 110 females, aged 61.

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Nanofibers produced by electrospinning are suitable options for slow-release materials. Diclofenac sodium (DS) is a nonsteroidal anti-inflammatory medication with a brief half-life that can serve as an effective sustained-release agent. This paper presents a novel method for producing DS-sustained release nanofibers by electrostatic spinning processes.

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Erythrodermic atopic dermatitis (EAD) and erythrodermic psoriasis (EP) are rare yet debilitating inflammatory skin disorders that propose challenges in diagnosis and discovering effective therapeutic targets. Despite their clinical and histological similarities, the underlying molecular mechanisms and systemic biomarkers of these diseases are substantially unclear. In this study, we sought to investigate the differential serum proteome of EP and EAD patients and identify biomarkers for these two subtypes of erythroderma.

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Stereo matching cost constrains the consistency between pixel pairs. However, the consistency constraint becomes unreliable in ill-posed regions such as occluded or ambiguous regions of the images, making it difficult to explore hidden correspondences. To address this challenge, we introduce an Error-area Feature Refinement Mechanism (EFR) that supplies context features for ill-posed regions.

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Background: Bawei Chenxiang Wan (BCW) is among the most effective and widely used therapies for coronary heart disease and angina pectoris in Tibet. However, whether it confers protection through a right-ventricle (RV) myocardial metabolic mechanism is unknown.

Methods: Male Sprague-Dawley rats were orally administrated with BCW, which was injected concurrently with a bolus of Sugen5416, and subjected to hypoxia exposure (SuHx; 5000 m altitude) for 4 weeks.

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Article Synopsis
  • - The study focuses on the use of minimally invasive surgical techniques for treating esophageal cancer, particularly highlighting the inflatable mediastinoscopic method and its modifications to reduce surgical trauma.
  • - A retrospective analysis of patients undergoing these techniques at a specific hospital showed that all surgeries were successful without needing to convert to open surgery, and there were no major differences in operation times or complications between the original and modified methods.
  • - The modified approach allowed for better mobilization of the esophagus in more patients, indicating it may offer improved outcomes while still being a safe and effective procedure.
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Background: Palmoplantar pustulosis (PPP) is a chronic inflammatory disease of ill-defined etiopathology. Recent studies have proposed complete blood count-based hematological parameters, such as neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR), as biomarkers to monitor disease status in many inflammatory diseases. This study aimed to analyze for the first time the clinical significance of hematological parameters, including NLR, monocyte/lymphocyte ratio (MLR), PLR, mean platelet volume (MPV), plateletcrit (PCT), and pan-immune-inflammation value (PIV) in PPP patients.

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Ovarian cancer (OC) ranks as the fifth leading cause of cancer-related death in women. The main contributors to the poor prognosis of ovarian cancer are the high rates of recurrence and metastasis. Studies have indicated a crucial role for hepatitis B virus X Ag-Transactivated Protein 8 (XTP8), a protein containing the DEP domain, in various cellular processes, including cell growth, movement, and differentiation, across several types of cancers.

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