Publications by authors named "Ning Su"
Purpose: Systemic inflammation biomarkers, derived from routine blood tests, have been demonstrated to be associated with prognosis of patients undergoing peritoneal dialysis (PD). However, studies focusing on the comparisons of their role on predictive efficacy for prognosis of PD patient are limited and results are inconsistent. The purpose of this study was to evaluate the prognostic value of various systemic inflammation biomarkers and to identify the optimal one in PD patients.
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- * The treatment showed a 37.5% objective response rate and an 85.0% disease control rate, with a median progression-free survival of 9.5 months and a 1-year overall survival rate of 73.3%.
- * Common severe side effects included hand-foot syndrome (22.5%) and oral mucositis (17.5%), while circulating tumor DNA (ctDNA) analysis indicated its potential as a predictive biomarker for treatment response and disease progression.
Article Synopsis
- MicroRNAs (miRNAs) are short non-coding RNAs that play a key role in regulating gene expression after transcription by binding to messenger RNAs (mRNAs) and inhibiting protein production.
- They are involved in crucial biological processes such as cell growth, differentiation, and the development of diseases like cancer.
- Methylation modifications of miRNAs can influence their function and effectiveness, and this review highlights new findings on how these modifications impact miRNA biogenesis and overall gene regulation.
Evaluation of cosmetic efficacy of lychee seed fermentation liquid.
Bioresour Bioprocess
October 2024
Article Synopsis
Article Synopsis
- The study investigates the relationship between the platelet-to-albumin ratio (PAR) and mortality risks in patients undergoing peritoneal dialysis (PD), focusing on cardiovascular disease (CVD) and overall mortality rates.* -
- Conducted with 2825 PD patients over an average follow-up of about 48 months, the research found that higher PAR levels are linked to a significant increase in the risk of both all-cause and CVD-related death.* -
- The results from statistical analyses support the conclusion that PAR can be a useful prognostic marker for predicting mortality outcomes in patients on PD, suggesting that monitoring PAR could improve patient management.*
Article Synopsis
- Gastrointestinal bleeding is a serious complication for peritoneal dialysis patients, linked to higher mortality rates and potentially exacerbated by elevated uric acid levels, which can also increase the risk of hemorrhagic stroke.
- The study involved 2,498 patients, creating two groups based on uric acid levels, and utilized various statistical methods to analyze the relationship between uric acid levels and gastrointestinal bleeding.
- Results indicated that higher uric acid levels increased the likelihood of gastrointestinal bleeding, with proton pump inhibitors showing potential to mitigate this risk among affected patients.