Luteolin attenuates neuronal apoptosis in the hippocampi of diabetic encephalopathy rats.

Luteolin (3',4',5,7-tetrahydroxyflavone) has powerful anti-apoptotic and antioxidant properties. This study aimed to investigate the effects of luteolin on hyperglycemia-mediated apoptosis in the hippocampi of rats with streptozotocin-induced diabetic encephalopathy after injection into the tail veins, and the molecular mechanisms involved. Biochemistry and terminal deoxynucleotidyl transferase mediated dUTP nick end labelling detection results showed that luteolin treatment (given twice daily for 15 days) significantly inhibited hyperglycemia-mediated apoptosis, decreased malondialdehyde levels and increased glutathione levels in the hippocampi of streptozotocin-induced diabetic rats.

Genetic differentiation of Trachurus japonicus from the Northwestern Pacific based on the mitochondrial DNA control region.

Trachurus japonicus is a pelagic fish widely distributed from China, Korea to Japan. To examine the gene flow of T. japonicus between Chinese and Japanese coastal waters, eight populations were collected for the present study.

[mRNA expression of telomere protection protein TIN2 and POT1 in bone marrow of patients with myelodysplastic syndrome].

This study was purposed to explore the relationship between the mRNA expression of telomere protection protein TIN2 and POT1 and the pathogenesis of myelodysplastic syndrome (MDS). The expression of TIN2 and POT1 genes at the mRNA levels were detected by real-time fluorescence quantitative PCR in 51 patients with MDS and 10 normal controls. The results showed that the mRNA expressions of TIN2 in RA/RARS/RCMD/MDS-U, RAEB-1 and RAEB-2 groups according to the World Health Organization criteria were significantly higher than that in the controls (P < 0.

[Expression and significance of neutrophil gelatinase-associated lipocalin in renal interstitial fibrosis in rats].

Objective: To explore the expression and significance of neutrophil gelatinase-associated lipocalin(NGAL)in renal interstitial fibrosis (RIF) in rats.

Methods: A total of 60 male Sprague-Dawley rats were randomly divided into 3 groups of sham operation (SOR), unilateral ureteral obstruction (UUO) and angiotensin-converting enzyme inhibitor (ACEI). The serum concentrations of NGAL and tumor necrosis factor-alpha (TNF-α) were detected by enzyme-linked immunosorbent assay (ELISA).

[Correlation between KRAS mutations and clinicopathologic features in colorectal carcinomas].

Objective: To investigate mutations of KRAS gene and clinicopathological characteristics of colorectal carcinomas (CRC) in Chinese.

Methods: Tumor cells were collected by microdissection from paraffin-embedded tumor specimens and adjacent normal colon tissues from 167 CRC patients. Genomic DNA was extracted and mutations of KRAS gene (codons 12 and 13) were detected by scorpions amplification refractory mutation system (Scorpions ARMS).

[Calcium hydroxide regulates bone sialoprotein gene transcription in human dental pulp cells].

Objective: To analyze the effects of calcium hydroxide [Ca(OH)2] on transcription of the bone sialoprotein (BSP) gene in human dental pulp cells.

Methods: Human dental pulp tissues were collected from extracted teeth for orthodontic reason. In cell culture media, different dose (0.

Effects of Electroacupuncture at Head Points on the Function of Cerebral Motor Areas in Stroke Patients: A PET Study.

Positron emission tomography (PET) is used to observe the cerebral function widely and is a good method to explore the mechanism of acupuncture treatment on the central nervous system. By using this method, we observed the cerebral function of 6 patients suffering from ischemic stroke after receiving EA treatment at Baihui(GV20) and right Qubin(GB7). The results were: (1) the glucose metabolism changed significantly on primary motor area (M1), premotor cortex (PMC), and superior parietal louble (LPs) bilaterally, as well as the Supplementary Motor Area (SMA) on the unaffected hemisphere right after the first EA treatment.

Compared study on the cellulose/CaCO3 composites via microwave-assisted method using different cellulose types.

The purposes of this study were to explore the influences of different cellulose types on the cellulose/CaCO3 composites, which were synthesized via the microwave-assisted method by using alkali extraction cellulose and microcrystalline cellulose, respectively. Experimental results demonstrated that the types of cellulose played an important role in the microstructure and morphologies of the cellulose/CaCO3 composites. The composites consisted of cellulose and pure phase CaCO3 (calcite).

Nanocomposites of cellulose/iron oxide: influence of synthesis conditions on their morphological behavior and thermal stability.

Nanocomposites of cellulose/iron oxide have been successfully prepared by hydrothermal method using cellulose solution and Fe(NO3)3·9H2O at 180 °C. The cellulose solution was obtained by the dissolution of microcrystalline cellulose in NaOH/urea aqueous solution, which is a good system to dissolve cellulose and favors the synthesis of iron oxide without needing any template or other reagents. The phases, microstructure, and morphologies of nanocomposites were characterized by X-ray powder diffraction (XRD), scanning electron microscopy (SEM), and energy-dispersive X-ray spectra (EDS).

Clinical study of distribution and drug resistance of pathogens in patients with severe acute pancreatitis.

Background: Previous researches about necrotic pancreatic tissue infections are numerous, but the study on systemic infection related to the severe acute pancreatitis (SAP) treatment period is limited. This study aimed to investigate the distribution and drug resistance of pathogenic bacteria in patients who had hepatobiliary surgery for SAP during the past three years.

Methods: A retrospective study was conducted on the distribution, category and drug resistance of pathogenic bacteria in patients who had hepatobiliary surgery for SAP from 2008 to 2011.

Correlation between ischemia-modified albumin and lipid levels in patients with acute cerebrovascular disease.

Acute cerebrovascular disease (ACVD) is associated with high morbidity and mortality rates, however, molecular markers to aid in its early detection are lacking. In this study, we examined the correlation between serum ischemia-modified albumin (IMA), a marker used to identify ischemic events in the heart, and blood lipids in patients with ACVD. Serum IMA levels were determined by enzyme-linked immuno-sorbent assay, and total cholesterol (TC), low-density lipoprotein (LDL), high‑density lipoprotein cholesterol (HDL) and triglyceride (TG) levels were determined biochemically in 62 patients with cerebral infarction (CI), 40 patients with intracerebral hemorrhage (ICH), 18 patients with subarachnoid hemorrhage (SAH) and 100 healthy individuals (controls).

Reply to "Comment on 'Analytical investigation of the open boundary conditions in the Nagel-Schreckenberg model' ".

Recent reports [N. Jia and S. Ma, Phys.

Isolation and characterization of hemicelluloses extracted by hydrothermal pretreatment.

The dewaxed sample from Triploid of Populus tomentosa Carr. was extracted by using organic alkaline solvent (Dimethylformamide, DMF) via hydrothermal pretreatment. Neutral sugar compositions and molecular weight analysis demonstrated that the hemicellulosic fractions with a higher Uro/Xyl ratio, namely the more branched hemicelluloses, had higher molecular weights.

N-Terminal domain of Bombyx mori fibroin mediates the assembly of silk in response to pH decrease.

Fibroins serve as the major building blocks of silk fiber. As the major component of fibroin, the fibroin heavy chain is a considerably large protein comprising N-terminal and C-terminal hydrophilic domains and 12 highly repetitive Gly-Ala-rich regions flanked by internal hydrophilic blocks. Here, we show the crystal structure of the fibroin N-terminal domain (FibNT) at pH 4.

The Arabidopsis J-protein AtDjB1 facilitates thermotolerance by protecting cells against heat-induced oxidative damage.

AtDjB1 belongs to the J-protein family in Arabidopsis thaliana. Its biological functions in plants are largely unknown. In this study, we examined the roles of AtDjB1 in resisting heat and oxidative stresses in A.

[The epidemiological study of work-related musculoskeletal disorders and related factors among automobile assembly workers].

Objective: To investigate the work-related musculoskeletal disorders among automobile assembly workers, to discusses the related risk factors and their relationship.

Method: The selected 1508 automobile assembly workers from a north car manufacturing company were regarded as the study object. The hazard zone jobs checklist, Nordic musculoskeletal symptom questionnaire (NMQ) and pain questionnaire were used to perform the epidemiological cross-sectional and retrospective survey and study for the General status, awkward ergonomics factors and related influencing factors, and musculoskeletal disorders of workers.

Perinatal outcomes and congenital abnormalities in the newborns of women affected by the 2009 pandemic influenza A (H1N1) in Beijing, China.

Objective: To investigate the pregnancy complications, perinatal outcomes, and congenital abnormalities (CAs) that occurred in Beijing, China, when pregnant women became infected with the 2009 pandemic influenza A (H1N1) (H1N1 pdm).

Methods: Pregnancy complications, perinatal outcomes, and CAs were compared among 3 groups of pregnant women. The 23 women in group 1 were confirmed to harbor viral RNA; the 23 in group 2 had serum levels of virus-specific antibodies against H1N1 pdm, meaning that they were suspected of being infected with the virus; and the 93 in group 3 had no detectable virus-specific antibodies.

Green microwave-assisted synthesis of cellulose/calcium silicate nanocomposites in ionic liquids and recycled ionic liquids.

Fabrication of biomass materials by a microwave-assisted method in ionic liquids allows the high value-added applications of biomass by combining three major green chemistry principles: using environmentally preferable solvents, using an environmentally friendly method, and making use of renewable biomass materials. Herein, we report a rapid and green microwave-assisted method for the synthesis of the cellulose/calcium silicate nanocomposites in ionic liquids and recycled ionic liquids. These calcium silicate nanoparticles or nanosheets as prepared were homogeneously dispersed in the cellulose matrix.

Traffic-light boundary in the deterministic Nagel-Schreckenberg model.

The characteristics of the deterministic Nagel-Schreckenberg model with traffic-light boundary conditions are investigated and elucidated in a mostly theoretically way. First, precise analytical results of the outflow are obtained for cases in which the duration of the red phase is longer than one step. Then, some results are found and studied for cases in which the red phase equals one step.

A phase II study of neoadjuvant chemoradiotherapy with oxaliplatin and capecitabine for rectal cancer.

Purpose: This study evaluated the efficacy and safety of neoadjuvant chemoradiotherapy with the XELOX regimen in rectal cancer patients.

Patients And Methods: Twenty-five patients with histopathologically confirmed and locally advanced rectal cancer (T3/T4 or N+) were enrolled in the study. Radiotherapy of 5000 cGy was delivered in 25 fractions of 200 cGy five times per week for a total of 5 weeks.

Viral shedding in Chinese young adults with mild 2009 H1N1 influenza.

Background: The duration of viral shedding and the transmission of 2009 H1N1 influenza among individuals, especially among the younger population with mild illness, are not well understood now. The aim of this study was to determine the viral shedding of the young adult patients with mild 2009 H1N1 influenza in China.

Methods: From September 2009 to January 2010, the clinical data and serial nasopharyngeal swabs of 67 patients with 2009 H1N1 influenza and 37 patients with seasonal influenza aged from 18 years to 35 years were collected.

Complete genome sequence of the bacterium Ketogulonicigenium vulgare Y25.

Ketogulonicigenium vulgare is characterized by the efficient production of 2KGA from L-sorbose. Ketogulonicigenium vulgare Y25 is known as a 2-keto-L-gulonic acid-producing strain in the vitamin C industry. Here we report the finished, annotated genome sequence of Ketogulonicigenium vulgare Y25.

[Colloidal gold and dot-ELISA rapid tests for screening influenza A virus].

Objective: To evaluate the diagnostic efficiency of colloidal gold and dot ELISA rapid tests in clinical screening of influenza A virus.

Methods: The pharyngeal swabs were collected from 297 outpatients suspected of influenza between June and October, 2009 for detection with colloid gold and dot ELISA rapid test, with real-time PCR as the golden methods. The discrepant results of colloid gold and dot ELISA methods were confirmed by sequencing, and the diagnostic efficiency of the two methods was evaluated.

Fast onset of action and the analgesic and sedative efficacy of essential oil from Rhizoma Chuanxiong after nasal administration.

In this study, the analgesic and sedative efficacy of Chuanxiong essential oil after nasal administration was compared with that of the commonly used oral administration route. The essential oil significantly reduced nociception only 5 min after nasal administration but not by i.g.