Importance: Childhood adverse experiences have been linked with long-term risk of cardiovascular disease (CVD), yet the transgenerational associations between interparental behaviors and CVD remain poorly understood.
Objectives: To explore the association between exposure to childhood interparental physical violence and the subsequent risk of CVD and to examine whether the association is modified by adult depressive symptoms.
Design, Setting, And Participants: This population-based cohort study included data from the China Health and Retirement Longitudinal Study (CHARLS), an ongoing study recruiting individuals aged 45 years or older, dated between June 1, 2011, and December 31, 2020, with a follow-up duration of 9 years.
Vessel scaffolds are crucial for treating cardiovascular diseases (CVDs). It is currently feasible to fabricate vessel scaffolds from a variety of materials using traditional fabrication methods, but the risks of thrombus formation, chronic inflammation, and atherosclerosis associated with these scaffolds have led to significant limitations in the clinical usages. Bioprinting, as an emerging technology, has great potential in constructing implantable vessel scaffolds.
View Article and Find Full Text PDFThis study investigates the differences in peripheral blood parameters between patients with non-neurosyphilis and neurosyphilis, aiming to identify potential serum biomarkers to predict the occurrence of neurosyphilis and avoid unnecessary lumbar punctures. A retrospective analysis was conducted on 110 HIV-negative syphilis patients in this study. We found that the serum homocysteine (Hcy) levels in the non-neurosyphilis group, asymptomatic neurosyphilis group, and symptomatic neurosyphilis group were 12.
View Article and Find Full Text PDFEthnopharmacological Relevance: Xanthohumol (XN), an isoprenylated flavonoid natural product found only in hops, possesses a variety of biological activities such as anticancer, anti-inflammatory, hepatoprotective, and anti-obesity.
Aim Of The Study: The aim of this study was to investigate the effects and mechanisms of XN on the treatment of colitis.
Materials And Methods: First, acute colitis was induced by using distilled water containing 3% DSS for 10 consecutive days.
Cancer has emerged as a significant threat that gravely endanger human health. Anti-tumor immunotherapy has now emerged as an important treatment for cancer. However, immunosuppressive tumor microenvironment limits the antitumor immunity.
View Article and Find Full Text PDFThe natural process of photosynthesis involves a series of consecutive energy transfers, but achieving more steps of efficient energy transfer and photocatalytic organic conversion in artificial light-harvesting systems (ALHSs) continues to pose a significant challenge. In the present investigation, a range of ALHSs showcasing a sophisticated three-step energy transfer mechanism is designed, which are meticulously crafted using pillar[5]arene (WP[5]) and p-phenylenevinylene derivative (PPTPy), utilizing host-guest interactions as energy donors. Three distinct types of fluorescent dyes, namely Rhodamine B (RhB), Sulforhodamine 101 (SR101), and Cyanine 5 (Cy5), are employed as acceptors of energy.
View Article and Find Full Text PDFMicrobiol Resour Announc
December 2024
strain m318 is an arsenite-oxidizing rhizobacterium isolated from the rhizosphere of an arsenic hyperaccumulator plant, beneficial for arsenic phytoremediation. Here, we report the complete genome sequence of this strain, which consists of a circular chromosome assembled using long reads sequenced on Nanopore and polished with Illumina paired-end reads.
View Article and Find Full Text PDFDiabetic retinopathy (DR) is the major ocular complication of diabetes caused by chronic hyperglycemia, which leads to incurable blindness. Currently, the effectiveness of therapeutic interventions is limited. This study aimed to investigate the function of piezo-type mechanosensitive ion channel component 1 (PIEZO1) and its potential regulatory mechanism in DR progression.
View Article and Find Full Text PDFAluminum-air battery has the advantages of high energy density, low cost and environmental protection, and is considered as an ideal next-generation energy storage conversion system. However, the slow oxygen reduction reaction (ORR) in air cathode leads to its unsatisfactory performance. Here, we report an electrode made of N and Ni co-doped MnO nanotubes.
View Article and Find Full Text PDFBackground: The metastasis of hepatocellular carcinoma (HCC) leads to a poor prognosis, wherein the activation of Notch1 is an essential contributor. Cepharanthine (Cep) has been identified for its effective antiviral function and versatile intracellular targets. Our previous study has only reported the anti-cancer efficacy of Cep in lung cancer, without an in-depth exploration.
View Article and Find Full Text PDFColloids Surf B Biointerfaces
January 2025
Combined chemo-phototherapy has shown considerable advantages and potential in cancer treatment. For this purpose, self-assembled nanoparticles by gambogic acid (GA) and IR780 (referred to as GA-IR780 NPs) were prepared. Herein, GA, an active compound derived from Garcinia hanburyi Hook.
View Article and Find Full Text PDFMature embryos are the main explants of tissue culture used in rice transgenic technology. However, the mechanism of mature embryo callus formation remains unclear. In this study, a microRNA-mediated gene regulatory network of rice calli was established using degradome sequencing.
View Article and Find Full Text PDFBacterial infections pose a great threat to human health. Therefore, the development of new antibacterial agents or methods is in urgent need. In this study, we prepared polytannic acid (pTA)-coated PLGA nanoparticles decorated with Dermaseptin-PP (Der), an antimicrobial peptide (AMP), on the surface to obtain PLGA-pTA-Der.
View Article and Find Full Text PDFThe process data in computer-based problem-solving evaluation is rich in valuable implicit information. However, its diverse and irregular structure poses challenges for effective feature extraction, leading to varying degrees of information loss in existing methods. Process-response behavior exhibits similarities to textual data in terms of the key units and contextual relationships.
View Article and Find Full Text PDFJ Med Microbiol
September 2024
Unlabelled: The number of pediatric respiratory tract infection cases in China has significantly increased this year, and is one of the main pathogens. This study aimed to investigate the epidemiological characteristics of in children in the Anhui region and to provide evidence for the prevention and control strategies of in children in this region. A total of 66,488 pediatric patients with respiratory tract infection were enrolled from January 2015 to November 2023 in this study.
View Article and Find Full Text PDFLiSrSiO:Eu is a promising substitute for traditional YAlO:Ce (YAG:Ce) owing to its strong orange-yellow emission of 4f-5d transition originating from Eu dopant, covering the more red-light region. However, its inevitable luminescence thermal quenching at high temperatures and the self-oxidation of Eu strongly impede their applications. Their remediation remains highly challenging.
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