Laryngeal morphologic changes and epidemiology in patients with inhalation injury: a retrospective study.

Background And Objectives: Laryngeal morphologic changes are important in risk assessment of upper airway obstruction (UAO) after inhalation injury. This retrospective study evaluates the clinical application of laryngeal burn classification system.

Materials And Methods: Clinical data from January 1999 to June 2013 were analyzed retrospectively.

Pathological changes of the three clinical types of laryngeal burns based on a canine model.

Objective: The study was designed to examine pathological changes of inhalational laryngeal burns of three clinical types: congestive, oedematous and obstructive.

Methods: A total of 18 healthy, male, adult Beagle dogs were randomly assigned to inhale hot dry air at room temperature (group C), 80°C (Group 1), 160°C (Group 2) or 320°C (Group 3) for 20min to induce inhalation injury. Each larynx was evaluated and scored based on the 'clinical scoring and typing system of laryngeal burns at early stage'.

Firework injuries at a major trauma and burn center: A five-year prospective study.

Background And Objective: In China, fireworks are an integral part of the celebration of the annual Spring Festival, but the number of injuries associated with their private use seen in emergency rooms increases dramatically. To raise awareness and help guide future prevention practices in this city, we investigated the epidemiology of firework-related injuries presented at our trauma and burn center in Beijing during the Spring Festivals of 2007-2011.

Methods: Patients were interviewed using a pre-coded questionnaire to elicit information regarding age, gender, causes, injured body part, type of injury, diagnosis, and disposition.

Circulational heat dissipation of upper airway: Canine model of inhalational thermal injury.

Background: The upper airway has powerful heat-absorbing ability, in which the blood circulation may play an important role.

Objective: This study aimed to explore the circulational heat-dissipating ability, and to investigate the contribution of blood circulation to the heat-absorbing ability of upper airway.

Methods: 18 adult, male Beagle dogs were divided into three groups to inhale thermal dry air of 70-80°C, 150-160°C or 310-320°C for 20min.

[Repair of circumferential wound in the wrist region due to high-voltage electrical burn using combined abdominal axial pattern flaps].

Objective: To explore the method for repairing circumferential wound in the wrist region due to high-voltage electrical burn.

Methods: Six patients with circumferential wound in the wrist region after high-voltage electrical burn were admitted to our hospital from January 2009 to December 2011. After debridement, wounds in the wrist were repaired with combined abdominal axial pattern flaps.

Repairing proximal and middle lower-leg wounds with retrograde sartorius myocutaneous flap pedicled by perforating branches of medial inferior genicular artery or posterior tibial artery.

Background And Objectives: The blood supply of the lower one-third of the sartorius muscle is mainly provided by the descending genicular artery (saphenous artery). The terminal branches of the saphenous artery, together with the perforators of the posterior tibial artery and medial inferior genicular artery, form a stable and rich anastomotic network in the genus inferior medialis. Based on this anatomy, we designed a retrograde sartorius myocutaneous flap to repair wounds in the proximal and middle thirds of the lower leg.

Epidemiology of 1974 burn patients at a major burn center in Beijing: a nine-year study.

To date, little epidemiological data are available on burns in China. This study describes the characteristics of burn patients admitted to a major burn center in Beijing to show trends in admission and outcomes in burned patients to share information about the current state of care for burned patients in our burn center. A retrospective study on 1974 burn patients admitted to Jishuitan Hospital in Beijing was conducted during the 9-year period from 2000 to 2008, and data were collected on age, gender, TBSA, etiology, length of hospital stay, mortality, and inhalation injury.

Temperature distribution in the upper airway after inhalation injury.

Objective: The aim of the study was to establish an animal model of laryngeal burn and to investigate the temperature distribution of heated air in the upper airway.

Methods: The animal model was established by inhalation of dry heated air at 80, 160 and 320 °C in 18 healthy, male, adult hybrid dogs. Time for inducing injury was set at 20 min.

Large-area burns with pandrug-resistant Pseudomonas aeruginosa infection and respiratory failure.

Background: Infection due to pandrug-resistant Pseudomonas aeruginosa (PDRPA) has become a challenge in clinical practice. The aim of this research was to summarize the treatment of large-area burns (60% - 80%) with PDRPA infection and respiratory failure in our hospital over the last two years, and to explore a feasible treatment protocol for such patients.

Methods: We retrospectively analyzed the treatment of five patients with large-area burns accompanied by PDRPA infection and respiratory failure transferred to our hospital from burn units in hospitals in other Chinese cities from January 2008 to February 2010.

Evaluation of the cytotoxicity of cell free dermal substitutes using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide method.

Background: The cytotoxicity of dermal substitutes may be increased by the very processes used to deplete the cells. The present research aimed to investigate the method for monitoring the cytotoxicity of cell-free dermal substitutes using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) method.

Methods: The cytotoxicity of four dermal substitutes was evaluated using the MTT method according to the standards set by the Chinese State Food and Drug Administration (SFDA).

[Quantification of type I and III collagen content in normal human skin in different age groups].

Objective: To quantify the content of type I, III collagen and their ratio in normal human skin of different age, and to explore the regulation of changes.

Methods: The normal human skin specimens were obtained from 6 spontaneously aborted fetus and 56 burn patients of different ages, including infants (newborn -3 years), pre-school group ( > 3, < or =7 years), adolescent group ( >7, < or = 18 years), youth and middle age group ( > 18, < or = 50 years), and elderly group ( > 50 years), were studied. The total collagen content were determined by hydroxyproline method.