[Modern aspects of pathogenesis of the trauma of the spinal cord and trunks of peripheral nerves].

In pathogenesis of the traumatic disease of the spinal cord, two mechanisms of the injuries of its neuronal apparatus are defined: primary (necrosis) and secondary (apoptosis). In the work a participation of a number of internal causes in the progression of apoptosis in injury of the spinal cord and peripheral nerve trunks, the role of those remains little-studied up to date, is discussed.

Experimental validation of direct long electrostimulation after neurotransplantation of the peripheral nerves.

Effects of direct long-term electric stimulation on the growth of the sciatic nerve regenerating axons through autoneurotransplants were studied in rabbits and an optimal electrostimulation method was developed.

[Changes in the activities of oxidoreductases, content of malondialdehyde and medium weight molecules in the blood of patients with craniocerebral injuries of different severity].

Biochemical changes are determined by the severity of craniocerebral injury. Twenty-four hours after the injury the activity of succinate dehydrogenase in lymphocytes increases significantly in patients with brain concussion and contusion of medium severity. Glutamate dehydrogenase activity increases in patients with repeated brain concussion.

[The serotonin content of the blood plasma in patients with craniocerebral trauma of varying degrees of severity].

It is shown that 24 hours after closed craniocerebral trauma plasma serotonin significantly rises in patients with moderate brain concussion and contusion. In repeated brain concussion and severe contusion these changes were absent. This may be due to biochemical maladaptation.