Publications by authors named "Nina Yu Kushnarevich"
Article Synopsis
- Primary open-angle glaucoma (POAG) is a common cause of blindness, linked to increased intraocular pressure and damage to the optic nerve and retinal cells, making early detection crucial for preserving vision.
- Traditional diagnosis is challenging due to the disease's asymptomatic nature in its early stages, but recent research indicates that analyzing tear fluid (TF) for protein changes can provide valuable biomarkers.
- A new method using differential scanning fluorimetry (nanoDSF) identified distinct TF protein profiles in 311 patients, allowing for a 70% identification rate of POAG, while machine learning minimized false positives to 13.5%, revealing significant changes in specific proteins and ligands associated with glaucoma.
Purpose: To compare the effectiveness of transpalpebral scleral tonometry (TPST) and corneal pneumotonometry in children, and assess the discomfort level when measuring intraocular pressure (IOP) by these methods.
Methods: TPST using EASYTON tonometer (Russia) and pneumotonometry using Reichert 7 Non-contact AutoTonometer (USA) have been sequentially performed on 84 eyes (42 children aged 5-14, ave. 9.