Publications by authors named "Nina Wittorff Jensen"
Article Synopsis
- The wireless motility capsule (WMC) is a noninvasive, radiation-free tool designed to measure gut transit in response to different food types, specifically looking at a granola bar (SmartBar) and a mixed meal.
- The study aimed to compare the gastrointestinal transit and metabolic responses between the SmartBar and a standardized mixed meal in 14 healthy participants through blood samples and WMC measurements.
- Results showed that the mixed meal resulted in significantly longer gastric emptying times and higher levels of certain metabolites and hormones compared to the SmartBar, indicating the WMC's effectiveness for gut transit evaluation.
Gut-derived hormones have been suggested to play a role in bone homeostasis following food intake, although the associations are highly complex and not fully understood. In a randomized, two-day cross-over study on 14 healthy individuals, we performed postprandial time-course studies to examine the associations of the bone remodeling markers carboxyl-terminal collagen type I crosslinks (CTX) and procollagen type 1 N-terminal propeptide (P1NP) with the gut hormones glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide 1 (GLP-1), and peptide YY (PYY) using two different meal types-a standardized mixed meal (498 kcal) or a granola bar (260 kcal). Plasma concentrations of total GIP, total GLP-1, total PYY, CTX, and P1NP were measured up to 240 min after meal intake, and the incremental area under the curve (iAUC) for each marker was calculated.
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