Treatment of positive urine cultures in the neonatal intensive care unit: a guideline to reduce antibiotic utilization.

Background: The pediatric definition of bacterial urinary tract infection (UTI) is >50,000 colony forming units (CFU) of a single organism on catheterized culture or 10,000-50,000 CFU with pyuria on urinalysis.

Local Problem: The diagnosis of UTI in our NICU is clinician-dependent and not based on the accepted pediatric definition.

Methods: A retrospective review of positive urine cultures between 2015 and 2017 was performed.