Publications by authors named "Nina Perry"
Supports for adaptive functioning in individuals with neurodevelopmental conditions (NDCs) is of umost importance to long-term outcomes. Artificial intelligence (AI)-assistive technologies has enormous potential to offer efficient, cost-effective, and personalized solutions to address these challenges, particularly in everday environments. This systematic review examines the existing evidence for using AI-assistive technologies to support adaptive functioning in people with NDCs in everyday settings.
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- The review analyzed 180 studies on executive function (EF) delays in children with neurodevelopmental conditions (NDCs), investigating whether these delays are a common feature across different NDCs.
- Results showed a moderate effect size of EF delays in children with NDCs compared to controls, with bigger delays observed in those with multiple comorbidities and specific conditions like ADHD and autism.
- The findings endorse the idea that EF delays are transdiagnostic, suggesting implications for understanding brain development and improving early interventions for children affected by NDCs.
Introduction And Aims: There is emerging evidence that heavy long-term alcohol consumption may alter the neuroimmune profile. We conducted a meta-analysis of the association between alcohol use disorder (AUD) and the extent of neuroinflammation using cerebrospinal (CSF), PET (Positron Emission Tomography), and postmortem studies.
Design And Methods: A comprehensive search of electronic databases was conducted using the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) for AUD-related terms in combination with neuroinflammatory markers and cytokine- and chemokine-related terms for CSF, PET, and postmortem studies.
Three-dimensional (3D) structured illumination microscopy (SIM) allows imaging of fluorescently labelled cellular structures at higher resolution than conventional fluorescence microscopy. This super-resolution (SR) technique enables visualization of molecular processes in whole cells and has the potential to be used in conjunction with electron microscopy and X-ray tomography to correlate structural and functional information. A SIM microscope for cryogenically preserved samples (cryoSIM) has recently been commissioned at the correlative cryo-imaging beamline B24 at the UK synchrotron.
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