Machine learning modeling and additive explanation techniques for glutathione production from multiple experimental growth conditions of Saccharomyces cerevisiae.

Glutathione (GSH) production is of great industrial interest due to its essential properties. This study aimed to use machine learning (ML) methods to model GSHproduction under different growth conditions of Saccharomyces cerevisiae, namely cultivation time, culture volume, pressure, and magnetic field application. Different ML and regression models were evaluated for their statistics to select the most robust model.

Optimization-based artificial neural networks to fit the isotherm models parameters of aqueous-phase adsorption systems.

An artificial neural network (ANN) hybrid structure was proposed that, unlike the standard ANN structure optimization, allows the fit of several adsorption curves simultaneously by indirectly minimizing the real output error. To model a case study of 3-aminophenol adsorption phenomena onto avocado seed activated carbon, a hybrid ANN was applied to fit the parameters of the Langmuir and Sips isotherm models. Network weights and biases were optimized with two different methods: particle swarm optimization (PSO) and genetic algorithm (GA), due to their good convergence in large-scale problems.