Publications by authors named "Nina Khera"
Article Synopsis
- Despite advancements in biomedical technologies, cardiovascular disease continues to be the leading cause of death, largely because current treatments overlook the effects of aging.
- A proposed model suggests that cell aging, particularly through processes like telomerase inactivation, leads to tissue changes that contribute to age-related cardiovascular issues affecting various heart and blood vessel cells.
- The model indicates that understanding the connection between risk factors and clinical outcomes can lead to more effective therapies, such as telomerase gene therapy, which may revolutionize treatment in cardiovascular medicine.
Children are known to be better protected from COVID-19 than adults, but their susceptibility patterns and the risk relative to other diseases are insufficiently defined. Here, we found that the COVID-19 mortality rate is U-shaped in childhood: it initially decreases, reaching the minimum at the ages 3-10 years, and then increases throughout life. All-cause mortality and mortality from other diseases, such as pneumonia and influenza, show a similar pattern; however, childhood mortality rates from COVID-19 are considerably lower than from other diseases, with the best relative protection achieved at the youngest ages.
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