Publications by authors named "Nina Kager"
Article Synopsis
- A controlled trial with 8 participants evaluated the effects of 225 g/day of spinach on DNA stability and biochemical health indicators over 16 days.
- Despite no reduction in overall DNA damage, specific types of oxidative DNA damage showed improvement after initial and continuous spinach intake, indicating potential protective effects.
- Spinach consumption was linked to increased folate levels and decreased homocysteine levels in the blood, suggesting that eating spinach may help prevent oxidative damage to DNA and improve certain health markers.
Coffee is among the most frequently consumed beverages worldwide and epidemiological studies indicate that its consumption is inversely related to the incidence of diseases in which reactive oxygen species (ROS) are involved (liver cirrhosis, certain forms of cancer and neurodegenerative disorders). It has been postulated that antioxidant properties of coffee may account for this phenomenon. To find out if consumption of paper filtered coffee which is the most widely consumed form in Central Europe and the US protects humans against oxidative DNA-damage, a controlled intervention trial with a cross-over design was conducted in which the participants (n=38) consumed 800ml coffee or water daily over 5 days.
View Article and Find Full Text PDFScope: Coffee is among the most frequently consumed beverages. Its consumption is inversely associated to the incidence of diseases related to reactive oxygen species; the phenomenon may be due to its antioxidant properties. Our primary objective was to investigate the impact of consumption of a coffee containing high levels of chlorogenic acids on the oxidation of proteins, DNA and membrane lipids; additionally, other redox biomarkers were monitored in an intervention trial.
View Article and Find Full Text PDFBackground: Consumption of green tea (GT) is associated with decreased incidences of specific forms of cancer in humans and it was postulated that its antioxidant (AO) properties may account for these effects. The evidence for AO effects of GT is mainly based on the results from in vitro experiments and on animal studies in which protection against chemically induced damage was monitored.
Aim Of The Study: The goal of the study was the investigation of the prevention of strand breaks and DNA migration attributable to endogenous oxidation of bases by GT extract (GTE) in inner organs and lymphocytes of untreated rats.