Publications by authors named "Nina Bisko"

Metallic nanoparticles potentially have wide practical applications in various fields of science and industry. In biosensorics, they usually act as catalysts or nanozymes (NZs) and as mediators of electron transfer. We describe here the development of amperometric biosensors (ABSs) based on purified oxidases, synthesized nanoparticles of CuCe (nCuCe), and micro/nanoporous gold (pAu), which were electro-deposited on a graphite electrode (GE).

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Article Synopsis
  • Endogenous cytokinins in medicinal mushrooms Hericium coralloides and Fomitopsis officinalis were identified using advanced chromatography techniques, revealing species-specific traits especially high levels of zeatin-type cytokinins and isopentenyladenine.
  • Purified cytokinin fractions from both mushroom species displayed cytotoxic effects on HepG2 tumor cells, promoting increased apoptosis and glucose uptake, with H. coralloides exhibiting more pronounced effects compared to F. officinalis.
  • The study suggests that the extraction methods of cytokinins are crucial for developing pharmacologically active drugs, highlighting the potential of these mushroom extracts as anticancer agents.
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The milky white mushroom, Calocybe indica Purkay & A. Chandra, is a tropical species not commercially cultivated in Europe. The influence of casing and scratching treatments on productivity, morphological characteristics, and nutritional contents were investigated during the cultivation of C.

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Mushrooms are known to produce phytohormones, in particular cytokinins. Here we studied in vitro production of cytokinins in medicinal mushrooms. Cytokinins were identified and quantified in mycelial biomass of 13 species by using high-performance liquid chromatography-mass spectrometry.

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The article presents the results of the investigation of the effect of biomass powder of the fungus Ganoderma lucidum on T-cell-mediated immunity in normal and immunosuppressed mice CBA/Ca. Delayed-type hypersensitivity assay was used. Experimental immunodeficiency was established with intraperitoneal injection of the immunosuppressant cyclophosphamide at a single dose of 150 mg/kg on the first day of the experiment.

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The content of proteins, lipids, and amino and fatty acids was investigated in mycelium and culture broth of medicinal mushrooms Cordyceps sinensis, Pleurotus ostreatus, and Schizophyllum commune. Seven essential amino acids were present in the proteins of all mushroom samples, with aspartic (6.34%-14.

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