Amputation Versus Limb-Salvage Surgery as Treatments for Pediatric Bone Sarcoma: A Comparative Study of Survival, Function, and Quality of Life.

Background: Pediatric appendicular bone sarcomas, including osteosarcoma and Ewing's sarcoma, are rare but aggressive malignancies that have a profound impact on survival, physical function, and quality of life (QoL). Treatment options usually involve either limb-salvage surgery (LSS) or amputation (AMP), although evidence about outcomes among these approaches is still limited.

Methods: A retrospective cohort study was conducted involving pediatric cases treated for appendicular bone sarcomas between 2000 and 2021 at the Instituto Português de Oncologia de Lisboa (IPOL), a Portuguese oncology center in Lisbon.

Anatomical implications of posterior cephaloceles in the dural venous sinuses.

Objective: To analyze the venous anatomy of the dural sinuses of patients with posterior encephaloceles, in order to formulate anatomical patterns which can ensure safer surgery.

Methods: This is a retrospective study, analyzing eight patients diagnosed with posterior encephalocele throughout 1 year.

Results: Eight patients with cephaloceles were evaluated in our study from January 2017 to January 2018.

What are the most frequent diagnoses in adolescence? The reality of an Adolescent Medicine Clinic.

Objective: To characterize the care flow and the primary diagnoses of an Adolescent Medicine Clinic.

Methods: A retrospective descriptive study, with analysis of clinical processes of adolescents (10-18 years) seen at the Adolescent Medicine Clinic, from January 2006 to December 2013. The following variables were analyzed: sex, age, number of visits, referring service and primary diagnoses according to the International Statistical Classification of Diseases and Related Health Problems.