Methemoglobinemia due to ingestion of at most three pills of pyridium in a 2-year-old: case report and review.

Pyridium (phenazopyridine HCl) is a commonly prescribed medication in the treatment of urinary tract infections and is known to cause methemoglobinemia in excessive doses. We report the case of a 2-year-old child who ingested a maximum of three 200-mg tablets (approximately 50 mg/kg) of pyridium and yet developed cyanosis and methemoglobinemia (29.1%), resulting in methylene blue therapy.

Point-of-care testing for drugs of abuse in an urban emergency department.

Point-of-care testing (POCT) has been used for illicit substance screening in several settings, primarily in law enforcement and drug treatment centers. In this study, we evaluate the use of this screening approach in the emergency department (ED) of a tertiary-care, urban medical center. Aliquots of urine specimens were tested simultaneously by a POCT device (OnTrak) and by a laboratory-based screening system (Triage).