Publications by authors named "Nimmagadda Ajit"

Prostate cancer is a common malignancy affecting elderly males. Generally, prostate cancer metastases to lymph nodes and skeletal lesions. Brain metastasis from prostate cancer is an uncommon phenomenon.

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Leptomeningeal carcinomatosis is a manifestation in which tumor cells migrate into meninges. Breast carcinoma presenting with leptomeningeal metastases is a rare phenomenon that can occur in an isolated form as well as with coexistent parenchymal brain metastases. The gold standard for diagnosis is cerebrospinal fluid analysis, while contrast-enhanced magnetic resonance imaging is the most commonly used imaging modality.

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Background: Diabetes mellitus is a common lifestyle disease where patients suffer from gastric dysmotility, which is usually underdiagnosed. The aim of this study was to evaluate the utility of Tc-99m sulfur colloid-labeled meal gastric emptying scintigraphy in Type 2 diabetic patients.

Methods: A total of 43 patients and 30 controls, satisfying the inclusion criteria from March 2019 to August 2020, were included.

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Purpose Of The Study: Renal mass lesions in majority of the cases are due to malignant etiology and about one-third of them are reported with metastatic lesions at the time of presentation. Thus proper investigational workup is needed for staging and thereby treatment planning. The current fluorine18 fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (F18-FDG PET/CT) study was designed to characterize renal mass lesions metabolically and identifying other metabolically active lesions in the body suggesting metastatic disease.

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Tuberculosis (TB) is chronic granulomatous infection caused by bacteria, , which primarily involves the lungs. Abdominal TB is an extrapulmonary disease which can mimic malignancy, especially in women with ascites, weight loss, and high cancer antigen-125 levels. Here, we report a case of young female, where clinical and radiological features were suggestive of ovarian malignancy.

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Objective: In the recent time, endoradionuclide therapy for metastatic castration-resistant prostate carcinoma employing Lu-PSMA-617 has yielded encouraging results and several clinical trials with the agent are currently ongoing. Routine preparation of Lu-PSMA-617 patient doses can be made simpler and convenient, if the ingredients essential for radiolabeling are made available in a ready-to-use lyophilized form.

Methods: PSMA-617 freeze-dried kit was formulated and used for the preparation of Lu-PSMA-617 clinical dose with high radiochemical purity using low/medium specific activity Lu.

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Background: Here, we present a retrospective study conducted from 2009 to 2018, which showed the presence of unilateral uptake of radioactive tracer on Tc thyroid scintigraphy scan in 15 patients with Graves' disease.

Materials And Methods: All these patients had either clinical features of Graves' disease or elevated thyroid hormone levels along with ultrasonographic features, showing either normal thyroid gland or diffuse thyroiditis. The scintigraphic features revealed increased uptake in one lobe of the thyroid gland with the other lobe being normal.

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Papillary carcinoma thyroid is the most common type of thyroid cancer. Papillary thyroid cancer metastasizes commonly to regional lymph nodes, distant organ involvement is to lungs and bone are rare and is associated with poor prognosis. Metastases to intra-abdominal organs are extremely rare.

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