Case Series: Mixed Infectious Keratitis by Pythium insidiosum and Fungal Species.

Significance: This case series is the first to illustrate mixed infection from Pythium sp. and fungal species in corneal ulcer.

Purpose: This case series aimed to alert all toward the possibility of both Pythium sp.

Rho-kinase inhibitors: Role in corneal endothelial disorders.

Purpose: This exhaustive review of published literature aims to put forth the current understanding, and experiences of the role Rho-kinase inhibitors play in the management of corneal endothelial disorders.

Methods: A meticulous search for PubMed and Medline databases was carried out using keywords 'rho-kinase inhibitors', 'corneal endothelial disorders', 'rho-kinase inhibitors in corneal endothelial disorders', and 'fuchs endothelial corneal dystrophy'. The articles published in last five years relevant to the area of interest were selected and compiled in a chronological order to write this review.

First reported case of corneal infection caused by .

A man in his 20s, with irritation, pain and photophobia in the left eye, was clinically diagnosed with herpes simplex virus nummular keratitis at our institute and advised topical antivirals and corticosteroids, causing resolution of active infiltrates. The infection recurred after 7 months and the patient did not respond to the previous regimen, so corneal scraping was sent for microbiological evaluation. Gram-positive bacilli grew on culture, which were identified as using VITEK 2 Compact system (bioMérieux, Marcy l'Etoile, France).