Suspension of oral hygiene practices highlights key bacterial shifts in saliva, tongue, and tooth plaque during gingival inflammation and resolution.

Experimentally induced gingivitis is associated with inflammatory and microbiological changes in an otherwise healthy subject, demonstrating the impacts of discontinuing oral hygiene routines. Understanding the bacterial dynamics during the induction and resolution of gingival inflammation will aid in the development of bacterial prognostic tests and probiotics for severe oral disease. We profiled the bacterial community in 15 healthy subjects who suspended all oral-hygiene practices for three weeks.

Primed PMNs in healthy mouse and human circulation are first responders during acute inflammation.

Polymorphonuclear neutrophils (PMNs) are the most abundant circulating leukocytes, and the first cells recruited to sites of tissue inflammation. Using a fixation method to preserve native CD marker expression prior to immunophenotyping, we identified a distinct population of "primed for recruitment" PMNs in healthy mouse and human blood that has high expression of adhesion and activation markers compared with the bulk resting-state PMNs. In response to acute tissue inflammation, primed PMNs (pPMNs) were rapidly depleted from the circulation and recruited to the tissue.

Role of oral health-related behaviors in education inequalities in chronic periodontitis among Sri Lankan men.

Aims: The aims of the present study were to determine education inequalities in chronic periodontitis (CP) among Sri Lankan men and whether oral health behaviors explain education inequalities in CP.

Methods: Data from 720 males who participated in a study to determine the prevalence of CP in 30-60-year-olds in Colombo district, Sri Lanka, were used for the present study. An interviewer administered a questionnaire obtained information about sociodemographics and oral health behaviors.