Optimization of 3D bioprinting of periodontal ligament cells.

Unlabelled: Three-dimensional (3D) bioprinting of cells is an emerging area of research but has been not explored yet in the context of periodontal tissue engineering.

Objective: This study reports on the optimisation of the 3D bioprinting of periodontal ligament cells for potential application in periodontal regeneration.

Methods: We systematically investigated the printability of various concentrations of gelatin methacryloyl (GelMA) hydrogel precursor using a microextrusion based three-dimensional (3D) printer.

Ciprofloxacin- and Fluconazole-Containing Fibrin-Nanoparticle-Incorporated Chitosan Bandages for the Treatment of Polymicrobial Wound Infections.

Polymicrobial wound infections often require high dosages of antibiotics and fungicides. However, prolonged antimicrobial therapies are associated with potential systemic side effects and an increased risk of the development of drug-resistant microbes. With this focus, we aimed at developing chitosan bandages loaded with antimicrobial drug (ciprofloxacin and fluconazole) nanoparticles for a sustained slow release of drugs.