Multiphysical analysis of nanoparticles and their effects on plants.

Nanoparticles are the magic bullets and at the leading edge in the field of nanotechnology, and their unique properties make these materials indispensable and superior in many areas, including the electronic field. Extensive applications of nanomaterials are incontrovertibly entering our living system. The increasing use of nanomaterials into the ecosystem is one of the crucial environmental factors that human being is facing.

Preclinical evaluation of drug in adhesive type ondansetron loaded transdermal therapeutic systems.

The in vivo assessment of percutaneous absorption of molecules is a very important step in the evaluation of any transdermal drug delivery system and a key goal in the design and optimization of transdermal dosage forms lies in understanding the factors that determine a good in vivo performance. The objective of the present investigation is to assess the in vivo performance of an optimized transdermal system of ondansetron hydrochloride in rabbits and to generate preclinical pharmacokinetic data. The pharmacokinetic performance of ondansetron hydrochloride following intravenous and transdermal administration was studied in rabbits following non compartmental pharmacokinetic analysis.