Systemic lupus erythematosus and avascular bone necrosis.

Two cases of systemic lupus erythematosus (SLE) developing avascular bone necrosis are described. One case had eight separate areas involved (shouldres, hips, knees and both distal tibiae), which is the largest number in a single case of SLE yet reported. In both cases, at the onset of symptoms of necrosis in a new area, the antinuclear factor increased markedly compared to the preceding level.

Behçet's syndrome with perforations of the colon.

A case of Behçet's syndrome with mucosal ulcerations of the ascending colon and three perforations of the caecum is described. It is the first documented case of this syndrome where colitis has occurred without concomitant rectal lesions. The reported cases of Behçet's syndrome with associated colonic lesions make up a heterogeneous group.

Molar pregnancy of hyperthyroidism.

A report on a patient with clinical hyperthyroidism associated with hydatidiform mole is presented. Some biochemical characteristics of the thyroid stimulator isolated from the tumour are discussed.

Malignant lymphoma and rheumatic symptoms.

A patient intially thought to have a connective tissue disease, later shown by biopsy to have Hodgkin's disease is described. The progress of her illness suggests that she is suffering from a connective tissue disease, too, or possibly secondary immune complex disease.