Ag Nanoclusters with Surface Azides as an Easily Functionalized Platform for Diverse Chemical Applications.

Modifying atomically precise nanocluster surfaces while maintaining the cluster core remains a key challenge. Herein, the synthesis, structure, and properties of two targeted Ag nanoclusters (NCs) with eight surface azide moieties, [CO@Ag(SBu)(m-N-CHCOO)(DMF)] (1-m) and [CO@Ag(SBu)(p-N-CHCOO)(DMF)] (1-p) are reported, where DMF is N,N-dimethylformamide. These AgNCs are designed to undergo cluster surface strain-promoted azide-alkyne cycloaddition (CS-SPAAC) reactions, introducing new functionality to the cluster surface.