Publications by authors named "Nils Froehlich"
Article Synopsis
- - Oxidized unsaturated fatty acids, known as eicosanoids and oxylipins, play a key role in various bodily functions including inflammation and blood flow regulation, and are of great interest in clinical lipidomics for their potential as health biomarkers.
- - This study used liquid chromatography-mass spectrometry to analyze 133 oxylipins in plasma samples, focusing on how sample handling and storage conditions affected their stability and concentration.
- - Findings showed that adding a radical scavenger improved sample reliability, and while oxylipin levels remained stable under certain conditions, longer storage times led to changes indicating residual enzyme activity, emphasizing the need for careful sample processing.
The carbon monoxide releasing molecule tricarbonyldichlororuthenium (CORM-2) displays protective actions like carbon monoxide. The molecular mechanism underlying this effect remains controversial. We hypothesized that CORM-2 mediates cytoprotection via induction of heat shock proteins through activation of p38 mitogen-activated kinase.
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