Angiolymphoid hyperplasia with eosinophilia presenting with peri-ocular swelling.

Angiolymphoid hyperplasia with eosinophilia and Kimura's disease share many clinical and histological features. Although they were once considered different stages of the same disease, they are now known to represent separate entities. Here a case is reported in a 14-year-old girl who presented with bilaterally symmetrical gradually progressive peri-ocular swelling involving both upper and lower eyelids of two months' duration.

Primary cold agglutinin disease: a case report.

Chronic cold agglutinin disease is a subgroup of auto-immune haemolytic anaemia. Primary cold agglutinin disease has traditionally been defined by the absence of any underlying or associated disease. It usually affects elderly.

A patient with recurrent attacks of drowsiness and lethargy--a diagnosis not to be missed.

Polyglandular auto-immune syndromes are uncommon constellation of organ specific auto-immune diseases, characterised by the existence of two or more endocrinopathies. Polyglandular autoimmune type II syndrome also known as Schmidt's syndrome is more common, comprising Addison's disease, auto-immune thyroid disease, type 1 diabetes mellitus and/or hypogonadism, pernicious anaemia, coeliac disease, vitiligo, hypophysitis, etc. Here a case of a 56-year-old man is reported with a prior history of hypothyroidism who presented with adrenal crisis.

Gitelman's syndrome presenting with hypocalcaemia, basal ganglia calcification and periodic paralysis.

Gitelman's syndrome (GS), also referred to as familial hypokalaemia-hypomagnesaemia syndrome, is an autosomal recessive renal tubular disorder characterised by hypokalaemic metabolic alkalosis, hypomagnesaemia and hypocalciuria. It is caused by a defect of the thiazide-sensitive sodium chloride co-transporter at the distal tubule. This condition was previously confused with Bartter syndrome.