Evaluation of the iodoacetic acid effects on adipose-derived mesenchymal stem cells and alteration of their osteogenic differentiation potential by inducing oxidative stress.

Drinking water disinfection byproducts (DBPs) can adversely affect human health. Iodoacetic acid (IAA) is a DBP associated with most cytotoxic, genotoxic, and mutagenic disorders. However, its effects on the osteogenic differentiation of adipose-derived mesenchymal stem cells, ADMSCs, remain unknown.